Vestibular evoked myogenic potential induced by bone-conducted stimuli in patients with conductive hearing loss.

Conclusions: Bone-conducted vestibular evoked myogenic potentials (B-VEMPs) showed high specificity for the presence of vertigo in patients with unilateral chronic otitis media (COM). These results suggest that vestibular function can be evaluated with B-VEMPs, even in patients with conductive hearing loss.

Objective: The purpose of this study was to investigate the VEMPs induced by bone-conducted stimuli (B-VEMPs) in patients with conductive hearing loss due to perforated COM.

A case of Churg-Strauss syndrome with refractory otitis media.

Objective: Churg-Strauss syndrome (CSS) is known as autoimmune vasculitis with peripheral eosinophilia after bronchial asthma and rarely has otological findings. We present a case of CSS with refractory otitis media and discuss the relationship between otological symptoms of CSS and eosinophilic otitis media.

Case Report: A 60-year-old woman had suffered from recurrent sinusitis for 8 years, and also otitis media with effusion for 4 months.

Immediate efficacy of the canalith repositioning procedure for the treatment of benign paroxysmal positional vertigo.

Objective: To study the immediate efficacy of the canalith repositioning procedure (CRP) in the treatment of benign paroxysmal positional vertigo.

Patients: Thirty-four patients with benign paroxysmal positional vertigo.

Intervention: Eighteen patients were treated with CRP (CRP group); 16 control patients did not receive CRP treatment (non-CRP group).

Immediate Efficacy of the Canalith Repositioning Procedure for the Treatment of Benign Paroxysmal Positional Vertigo.

OBJECTIVE:: To study the immediate efficacy of the canalith repositioning procedure (CRP) in the treatment of benign paroxysmal positional vertigo. PATIENTS:: Thirty-four patients with benign paroxysmal positional vertigo. INTERVENTION:: Eighteen patients were treated with CRP (CRP group); 16 control patients did not receive CRP treatment (non-CRP group).

Liposarcoma of temporal bone: a case report.

This is the third case report of liposarcoma of the temporal bone. A 69-year-old man complained of left otalgia, left otorrhea, and dizziness for several months, with a past history of tympanoplasty for cholesteatoma 28 years previously. Otoscopy revealed debris in the attic.

Localization of osteopontin at calcification sites of cholesteatoma: possible role as a regulator of deposition of calcium phosphate in the middle ear.

Objective: Recently, we showed that osteopontin (OPN), a major acidic phosphorylated glycoprotein of bone, participates in the pathological calcification that occurs as a result of chronic otitis media. To investigate the possibility of OPN as a common regulator of the pathological calcification in the middle ear, we here examined whether or not OPN is localized at the calcification sites of cholesteatoma, which is clearly different from chronic otitis media in the pathogenesis.

Methods: Middle ear tissues including cholesteatoma were obtained from 32 cases who underwent tympanoplasty.

Role of c-kit receptor tyrosine kinase-mediated signal transduction in proliferation of bile epithelial cells in young rats after ligation of bile duct: a study using Ws/Ws c-kit mutant rats.

Background/aims: Recently, it has been shown that the c-kit receptor tyrosine kinase (KIT) is expressed in the liver of young rats, and its expression is up-regulated in bile epithelial cells (BEC) after ligation of the common bile duct (BDL). To clarify a role of KIT in BEC, we examined whether BEC of Ws/Ws rats, whose KIT kinase activity was severely impaired, could proliferate in response to bile stasis after BDL.

Methods/results: When 2-week-old control normal (+/+) and Ws/Ws mutant rats underwent BDL, only a few BEC were found in the portal field of livers of Ws/Ws rats, whereas many BEC were found in that of +/+ rats.

Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1.

Organ-specific stem cells can be identified by the side population (SP) phenotype, which is defined by the property to effectively exclude the Hoechst 33342 dye. The ATP-binding cassette transporter ABCG2/BCRP1 mediates the SP phenotype. Because hepatic oval cells possess several characteristics of stem cells, we examined whether they have the SP phenotype using the 2-acetylaminofluorene/partial hepatectomy (PH) model.