Publications by authors named "Kohli A"

Article Synopsis
  • Neurosurgical anesthetic management involves careful planning, focusing on positioning during intubation, neuromonitoring, and selecting appropriate anesthetic agents to enhance patient outcomes.
  • A detailed case study of a 64-year-old woman with a cervical spine schwannoma showcases the implementation of video laryngoscopy to minimize neck movement and the use of propofol, remifentanil, and sevoflurane for continuous neuromonitoring.
  • The surgery was successful, with stable neurological function during the procedure, and the patient had no complications post-operation, being successfully extubated afterward.
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To evaluate the quality of life in the post maxillectomy patients due to Coronavirus disease 2019 (COVID-19) associated Mucormycosis (CAM) following rehabilitation with obturators. The study also described the management and treatment outcomes of CAM patients. The study included 80 confirmed patients of CAM.

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Debates on intellectual property rights and open source frequently stem from the business sector and higher education, where goals are typically oriented toward profit, academic status, credit, and/or reputation. What happens if we reconsider the ethics of intellectual property rights and open source when our driving motivation is advancing women's health and rights? How does this prioritization complicate our assumptions of copyright and open access? How can we embark on a journey that validates the complex realities of multiple stakeholders who have good intent, but do not always consider the unintended impacts and the broader power dynamics at play? This paper explores the tensions and nuances of sharing methodologies that aim to transform harmful gender norms in an ecosystem that does not always consider the complex challenges behind intellectual property and open-source material. As a thought-collective dedicated to using a feminist approach to unpack and promote the principles of ethical, effective, and sustainable scale, we hope to underscore how the current research and debates on intellectual property rights and open-source material have good aims but may also fall short in encompassing the realities of gendered social norms change in and with communities around the world.

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Article Synopsis
  • A clinical trial assessed the safety of the combination of casirivimab and imdevimab (CAS + IMD) in children with COVID-19.
  • The results showed that the treatment was well tolerated, similar to findings in adults, with minimal immune response side effects.
  • The study supports further development of advanced monoclonal antibodies for children at higher risk for COVID-19.
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Background: Because of its integrated design and possible benefits over conventional two-piece systems, single-piece implant systems have grown in favor in the field of dental implantology. There is, however, still a dearth of information about their long-term stability and clinical results. The purpose of this study was to assess the clinical results, such as implant survival rates, peri-implant tissue health, and marginal bone levels, to determine the long-term stability of single-piece implant systems.

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This article is meant to serve as a reference for radiologists, orthopedic surgeons, and other physicians to enhance their understanding of progressive collapsing foot deformity, also known as adult acquired flat foot deformity. Pathophysiology, imaging findings, especially on MRI and 3-dimensional MRI are discussed with relevant illustrations so that the readers can apply these principles in their practice for better patient managements.

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Background: Hymenoptera venom is one of the most frequent causes of anaphylaxis. Studies from adults indicate the clinical profiles and risk factors of Hymenoptera venom-induced anaphylaxis (VIA). Much less is known about pediatric VIA.

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To counter the rising incidence of diabetes and to meet the daily protein needs, we created low glycemic index (GI) rice varieties with protein content (PC) surpassing 14%. In the development of recombinant inbred lines using Samba Mahsuri and IR36 amylose extender (IR36ae) as parental lines, we identified quantitative trait loci and genes associated with low GI, high amylose content (AC), and high PC. By integrating genetic techniques with classification models, this comprehensive approach identified candidate genes on chromosome 2 ( spanning the region from 18.

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Immune reconstitution inflammatory syndrome (IRIS) is a potentially life-threatening phenomenon associated with the initiation of antiretroviral therapy in patients with acquired immunodeficiency syndrome due to a human immunodeficiency virus (HIV) infection. It is thought to be an exaggerated inflammatory response to an existing pathogen or even its antigen. We present a case of IRIS due to a non-tuberculous mycobacteria infection in a young patient with HIV infection who was recently started on therapy.

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Context: Worldwide malnutrition is identified as a major health and nutrition problem. Undernutrition contributes to an estimated 45% of child deaths globally. The prevalence of underweight among children in India is among the highest in the world.

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Purpose: Leg length discrepancy (LLD) and lower extremity malalignment can lead to pain and osteoarthritis. A variety of radiographic parameters are used to assess LLD and alignment. A 510(k) FDA approved artificial intelligence (AI) software locates landmarks on full leg standing radiographs and performs several measurements.

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Unlabelled: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common cause of hospital admissions. Coronavirus disease 2019 (COVID-19) has large impact on patients with pulmonary diseases. The purpose of the study is to evaluate the impact of COVID-19 on patients with AECOPD.

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Article Synopsis
  • The study investigates the relationship between motor function and Alzheimer's disease (AD) pathology, particularly looking at brain regions involved in motor control.
  • In a sample of 206 participants, findings revealed that increased neurodegeneration and AD biomarkers (like amyloid and tau) were linked to worse motor skills, specifically dexterity and walking speed.
  • The results suggest that declines in dexterity associated with AD could indicate potential areas for non-drug therapies to improve motor function in affected individuals.
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Pulmonary cryptococcosis is becoming increasingly common in immunocompetent hosts, manifesting with variable clinical presentations ranging from asymptomatic colonization to severe pneumonia. Radiological findings are non-specific, such as nodular infiltrates, mass-like lesions, and mediastinal lymphadenopathy. We present a case of a 61-year-old woman with pneumonia coinfected with , an unusual occurrence in an immunocompetent host and the first of its kind.

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Background: Medication prescribing by pharmacists is a task shifting approach to help ensure quality and accessibility of healthcare. In many countries, like the Netherlands, pharmacist prescribing is not legally ensured, and it is unknown what citizens think of its potential introduction.

Objective: To investigate citizen perspectives on the potential role of pharmacists in prescribing in primary care.

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Parietal bone hemangiomas represent a minority of diagnosed brain tumors. These lesions require careful management under anesthesia due to their vascularity and cranial location. We discuss a 31-year-old female with chronic headaches who underwent surgery for the removal of a large parietal bone hemangioma, necessitating considerations for stable hemodynamics, intracranial pressure (ICP), and bleeding risks.

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Background: As the number of genome-wide association study (GWAS) and quantitative trait locus (QTL) mappings in rice continues to grow, so does the already long list of genomic loci associated with important agronomic traits. Typically, loci implicated by GWAS/QTL analysis contain tens to hundreds to thousands of single-nucleotide polmorphisms (SNPs)/genes, not all of which are causal and many of which are in noncoding regions. Unraveling the biological mechanisms that tie the GWAS regions and QTLs to the trait of interest is challenging, especially since it requires collating functional genomics information about the loci from multiple, disparate data sources.

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Granulomatosis with polyangiitis (GPA) is a rare vasculitis that can pose a significant mortality risk given its multiorgan involvement and is the most common of the three anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides. Cardinal pathological features include necrotizing granulomas of the respiratory tract, small and medium vessel vasculitis, and glomerulonephritis. Early treatment is imperative to reduce permanent organ damage such as end-stage kidney disease.

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Rice germplasm collections contain vast reserves of genetic diversity but remain understudied. This Commentary highlights the effectiveness of mining genetic resources from germplasm as a means to overcome current yield constraints, using clustered-spikelet rice as an example.

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Aim: Single-tooth implant restorations, whether screw-retained or cement-retained, are essential for prosthodontic rehabilitation despite having low design flexibility, cosmetic appeal, and high 5-year survival rates.

Materials And Methods: A study involving 14 patients with missing mandibular first molars used 28 implants and cement-retained and screw-retained prostheses. Patients had a single edentulous gap, adequate dental hygiene, and sufficient bone volume at the implant site.

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Article Synopsis
  • * The LOTUS framework aims to enhance HCV treatment by emphasizing treatment as prevention for those who inject drugs, flexible adherence to medication, and minimal monitoring requirements.
  • * The article reviews existing literature on LOTUS, identifies knowledge gaps and barriers faced by healthcare providers, and proposes evidence-based solutions to improve HCV treatment outcomes.
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Unlabelled: Prevention of respiratory syncytial virus (RSV) infection is now a global health priority, with a long-acting monoclonal antibody and two RSV vaccines recently licenced for clinical use. Most licenced and candidate interventions target the RSV fusion (RSV-F) protein. New interventions may be associated with the spread of mutations, reducing susceptibility to antibody neutralization in RSV-F.

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Patella alta (PA) and patella baja (PB) affect 1-2% of the world population, but are often underreported, leading to potential complications like osteoarthritis. The Insall-Salvati ratio (ISR) is commonly used to diagnose patellar height abnormalities. Artificial intelligence (AI) keypoint models show promising accuracy in measuring and detecting these abnormalities.

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