Artificial intelligence-based analysis of lower limb muscle mass and fatty degeneration in patients with knee osteoarthritis and its correlation with Knee Society Score.

Purpose: Lower-limb muscle mass reduction and fatty degeneration develop in patients with knee osteoarthritis (KOA) and could affect their symptoms, satisfaction, expectation and functional activities. The Knee Society Scoring System (KSS) includes patient reported outcome measures, which is widely used to evaluate the status of knee function of KOA. This study aimed to clarify how muscle mass and fatty degeneration of the lower limb correlate with the KSS in patients with KOA.

Immune-related Adverse Event with Checkpoint Inhibitors Might Be an Emerging Underlying Disease of Steroid-related Osteonecrosis of the Femoral Head: A Case Report.

Introduction: Immune checkpoint inhibitors (ICIs) are increasingly being used in the treatment of advanced metastatic and immunogenic cancers. However, these therapies could cause immune-related adverse events (irAEs), which require high-dose glucocorticoid administration.

Case Report: A 52-year-old man with metastatic renal cell carcinoma received ICI therapy.

Femoral head translation in borderline and definite dysplastic hips during weight-bearing: 2D/3D image registration analysis.

Purpose: The aims of this study were to 1) assess femoral head translation during weight-bearing in symptomatic developmental dysplasia of the hip (DDH) and 2) compare it between borderline DDH and definite DDH.

Methods: The study included four individuals with borderline DDH and nine with definite DDH, scheduled for periacetabular osteotomy. Anteroposterior X-ray images of the hip joint were obtained in the standing position, and computed tomography images of the pelvis were obtained in the supine position.