Publications by authors named "Kohei Komaru"
Patients with borderline pulmonary hypertension (PH) often experience shortness of breath or exacerbation of PH during exercise, known as exercise-induced PH. However, the pathogenesis of exercise-induced post-capillary PH (post-EIPH) and its treatment strategies remain unclear. Recent guidelines and consensus documents have highlighted the benefits of sodium-glucose cotransporter-2 (SGLT2) inhibitors in heart failure and chronic kidney disease (CKD).
View Article and Find Full Text PDFBackground: Balloon pulmonary angioplasty (BPA) has exhibited substantial progress in the management of chronic thromboembolic pulmonary hypertension (CTEPH). However, nearly one-half of the patients with CTEPH experience persistent pulmonary hypertension after undergoing BPA, emphasizing the need for enhanced therapies.
Objectives: The authors sought to investigate the clinical significance of functional assessment-guided dilation of the pulmonary artery (PA) in patients with CTEPH undergoing BPA treatment.
Article Synopsis
- Hypereosinophilic syndrome (HES) involves high eosinophil levels, excluding other causes, and can lead to serious organ damage, including affecting coronary arteries and causing vasospastic angina (VSA).
- A 55-year-old woman with allergies and chest pain was found to have VSA due to spasms in her coronary arteries, with moderate eosinophilia during tests leading to a diagnosis of HES alongside eosinophilic pneumonia and chronic rhinosinusitis.
- Treatment with corticosteroids rapidly alleviated her symptoms and reduced eosinophil counts, highlighting the efficacy of this therapy for addressing both the VSA and underlying HES.