Publications by authors named "Koen M Hendriks"
Clonal Relationship Between Lichen Sclerosus, Differentiated Vulvar Intra-epithelial Neoplasia and Non HPV-related Vulvar Squamous Cell Carcinoma.
Anne-Floor W Pouwer Loes C G VAN DEN Einden Michelle VAN DER Linden Jayne Y Hehir-Kwa Jiangyan Yu Koen M Hendriks
Cancer Genomics Proteomics
September 2020
Background/aim: Differentiated vulvar intraepithelial neoplasia (dVIN) and lichen sclerosus (LS) can give rise to vulvar squamous cell carcinoma (VSCC), but genetic evidence is currently still limited. We aimed to determine genetic abnormalities in VSCC and backtrack these abnormalities in the dVIN and LS lesions.
Materials And Methods: DNA from VSCC and patient-matched dVIN and LS samples of twelve patients was collected.