Iatrogenic Adrenal Insufficiency Secondary to Combination Therapy with Elvitegravir/Cobicistat/Tenofovir Disoproxil Fumarate/Emtricitabine and Interlaminar Triamcinolone Injection in an AIDS Patient.

We report the first identified case of suspected iatrogenic adrenal insufficiency after an interlaminar injection of triamcinolone acetonide while on concomitant Stribild (elvitegravir 150 mg/cobicistat 150 mg/tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg [EVG/c/TDF/FTC]). A 49-year-old female with HIV on EVG/c/TDF/FTC therapy presented to our endocrinology clinic to be evaluated for suspected Cushing syndrome. Prior to presentation, the patient had been given 2 interlaminar spinal injections of triamcinolone.

The sellar/parasellar endocrinopathies: a brief clinical overview.

Endocrine disorders of the pituitary and other hypothalamic structures are reviewed. Anterior and posterior pituitary physiology is described as well as hormone-producing tumors that cause Cushing's disease, hyperprolactinemia, acromegaly-gigantism, and precocious and delayed puberty. The diagnosis and management of diabetes insipidus caused by hypothalamic-posterior pituitary disorders complete the overview.