Publications by authors named "Kodai Fukumoto"
Article Synopsis
- Researchers aim to create nanodevices that target specific organs or cells, which is a key goal in synthetic biology.
- Recent advancements in DNA nanotechnology, particularly DNA origami, have enabled the construction of robust nanodevices for delivering drugs to tumors, despite challenges like structural fragility and targeting.
- The study highlights the successful encapsulation of DNA origami in lipid-based nanoparticles, enhancing the delivery and effectiveness of genetic material (like mRNA and siRNA) in mouse organs, paving the way for better organ-specific gene expression control.
Cellular transport systems are sophisticated and efficient. Hence, one of the ultimate goals of nanotechnology is to design artificial transport systems rationally. However, the design principle has been elusive, because how motor layout affects motile activity has not been established, partially owing to the difficulty in achieving a precise layout of the motile elements.
View Article and Find Full Text PDFBending of cilia and flagella occurs when axonemal dynein molecules on one side of the axoneme produce force and move toward the microtubule (MT) minus end. These dyneins are then pulled back when the axoneme bends in the other direction, meaning oscillatory back and forth movement of dynein during repetitive bending of cilia/flagella. There are various factors that may regulate the dynein activity, e.
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