Publications by authors named "Ko Sudo"
Background: Polymyositis/dermatomyositis (PM/DM) patients often develop interstitial lung disease (ILD), which can lead to relapse despite anti-inflammatory treatments. This study aims to elucidate the clinical characteristics of relapses in PM/DM-associated ILD patients.
Methods: We gathered clinical data, including laboratory results, pulmonary function tests, chest high-resolution computed tomography findings from patients treated at Okinawa Chubu Hospital between January 1, 2010 and December 31, 2018.
Nitrogen-containing heterocycles possessing -alkenyl substituents are an important structural motif. However, the synthetic methods reported thus far cannot selectively synthesize the stereoisomer on the basis of the stereochemistry of the substituted alkenes. Herein, we report the stereoconvergent coupling of heterocycles and alkenyl halides consisting of a mixture of / stereoisomers, which selectively afforded the thermodynamically less stable -coupling product.
View Article and Find Full Text PDFBackground: Tranexamic acid is frequently reported to reduce bleeding-related complications in major surgery and trauma. We aimed to investigate whether tranexamic acid reduced hematoma size after percutaneous kidney biopsy.
Methods: We conducted a double-blind, parallel three-group, randomized placebo-controlled trial at a teaching hospital in Japan between January 2016 and July 2018.
[A case of right femoral artery thromboembolism in steroid-dependent nephrotic syndrome].
Nihon Jinzo Gakkai Shi
December 2016
Article Synopsis
- A 37-year-old man with a long history of minimal change nephrotic syndrome was hospitalized due to leg pain and complications from a relapse, including thromboembolism in major arteries.
- He received steroid pulse therapy and underwent thrombectomy but ultimately faced severe necrosis in his leg, leading to a below-knee amputation.
- The case highlights that arterial thrombosis, while rare, is a serious complication of nephrotic syndrome, suggesting that preventive anticoagulation should be considered for at-risk patients.