Publications by authors named "Knobf M"
Purpose: The study aimed to identify the profiles of psychological flexibility in patients with cervical cancer and how self-perceived burden networked to different psychological flexibility profiles.
Methods: The Personalized Psychological Flexibility Index and the Self-Perceived Burden for Cancer Patients were used to measure psychological flexibility and self-perceived burden in patients from the "Be Resilient to Cancer" project. Latent profile analysis was used to identify profiles and computer-simulated network analysis was conducted to determine if self-perceived burden networked to any of the psychological flexibility profiles.
Purpose: Fear of cancer recurrence (FCR) contributes to sleep problems and social support is a buffering factor in the literature. However, the moderating effect of social support between FCR and sleep quality is unclear.
Methods: The moderating role of social support was examined in a cohort of 460 breast cancer patients from the 2024 Be Resilient to Breast Cancer (BRBC) program from a microscopic perspective using moderated network analysis, and then assessed macroscopically by Johnson-Neyman and response surface analysis.
Purpose: This study aimed to explore symptom clusters and the inter-relationship of symptoms in esophageal cancer (EC) patients during the first week after surgery.
Methods: A cross-sectional survey across multiple centers was carried out using the EORTCQLQ-OES18. Patients with esophageal cancer within a week post-surgery were recruited from the "Be Resilient to Cancer" project in Guangdong, Hunan, and Sichuan provinces between January and September 2024.
Purpose: To pinpoint optimal interventions by dissecting the complex symptom interactions, encompassing both their static and temporal dimensions.
Methods: The study incorporated a cross-sectional survey utilizing the MD Anderson Symptom Inventory. Participants with breast cancer undergoing chemotherapy were recruited from the "Be Resilient to Breast Cancer" from April 2023 to June 2024.
Article Synopsis
- Integration is key in mixed methods research (MMR) but is often overlooked by researchers, who typically focus only on the final stages of analysis.
- The study aims to clarify the integration process in MMR using an example of sleep health research among women with breast cancer, highlighting four dimensions of integration that include philosophical assumptions, methods, and dissemination of findings.
- The results emphasize the importance of visual tools in analyzing and connecting quantitative and qualitative data to provide a deeper understanding of complex health issues, while also acknowledging the challenges of effective integration throughout the research process.
Article Synopsis
- The study aimed to analyze the health-related quality of life in women with metastatic breast cancer, focusing on factors influencing their experience over the last decade.
- An integrative review was conducted, screening 7,316 articles and selecting 25 studies that primarily involved non-Hispanic white women from the U.S. and Europe, using various assessment tools.
- Key findings indicated that physical and psychological symptoms significantly impact quality of life, highlighting the need for better symptom management and more diverse research to understand the effects of new therapies.
The longitudinal association between resilience and sleep quality in breast cancer.
Eur J Oncol Nurs
February 2025
Article Synopsis
- - The study aimed to evaluate how resilience affects sleep quality over the first six months in patients recently diagnosed with breast cancer, using data collected from 155 participants through well-established scales.
- - Researchers analyzed data from three timepoints (1, 3, and 6 months after diagnosis) and concluded that resilience positively influences sleep quality, with significant predictive relationships observed between the two variables.
- - Findings confirmed that higher resilience levels are linked to better sleep quality, suggesting that promoting resilience could be beneficial for breast cancer patients' overall well-being.
Purpose: To develop an in-depth understanding of the meaning of symptoms in the context of how women with stage I-III breast cancer in China cope with the effects of primary and adjuvant therapies for breast cancer.
Method: A qualitative descriptive approach was used. A purposive sample of women diagnosed with stage I-III breast cancer were recruited from the "Be Resilient to Breast Cancer" study between November 2023 and March 2024.
Parent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer.
J Pain Symptom Manage
November 2024
Context: Parent-clinician communication is essential for high-quality end-of-life (EOL) care in children with cancer. However, it is unknown how parent-clinician communication affects parents' experience in the first two years after their child's death.
Objectives: To examine the association between communication and prolonged grief among parents whose child died from cancer and to explore the mediation effect of preparation for EOL care.
Purpose: As a sign of femininity, impaired breast after surgery causes particularly confusion for patients with breast cancer resulting in increased body image distress, which has negative impacts on sleep quality. And self-efficacy enables patients to use positive and effective coping strategies to maintain a favorable night's sleep. Therefore, our study is to explore the heterogeneity in body image experienced by patients with breast cancer and to examine the mediation effects of self-efficacy between body image and sleep quality.
View Article and Find Full Text PDFThe purpose of this explanatory sequential mixed methods study was to examine parenting outcomes and experiences over time among marginalized adolescent mothers enrolled in randomized clinical trials (RCT) between 2002 and 2016 testing Minding the Baby® (MTB), an early home visiting program. The quantitative phase examined associations between measures of maternal experiences and parenting outcomes from 71 participants 2-8 years since RCT completion. MTB mothers reported less hostile parenting and fewer child behavior problems.
View Article and Find Full Text PDFPurpose: It was designed to identify the symptom clusters and sentinel symptoms among patients with breast cancer receiving chemotherapy at the community level, and to explore core and bridge symptoms at the global level.
Methods: A cross-sectional survey was conducted using the MD Anderson Symptom Inventory. Patients with breast cancer receiving chemotherapy, recruited from the "Be Resilient to Breast Cancer" project between January 2023 and December 2023, were included in the study.
Background: Patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) experience unpredictable disease trajectories and high prognostic uncertainty, which serve as barriers to patient-clinician communication about prognosis and their values and preferences for the future in the event of worsening health. Little is known about patients' day-to-day lived experiences and how this shapes their willingness to engage in such conversations.
Objectives: To explore participant perspectives on living with their illness and patient-clinician communication about prognosis and the future.
Purpose: Whether brain connectomics can predict 1-year decreased Quality of Life (QoL) in patients with breast cancer are unclear. A longitudinal study was utilized to explore their prediction abilities with a multi-center sample.
Methods: 232 breast cancer patients were consecutively enrolled and 214 completed the 1-year QoL assessment (92.
Purpose: Stigma, a subjective internal shame, arises from the association of cancer with death. Sleep quality can be considered a product of stigma. However, the extent of overlap or difference between the two remains unclear.
View Article and Find Full Text PDFPurpose: This study was designed to explore the impact of a new cancer diagnosis on resilience of patients and whether the resilience patterns could predict Quality of Life (QoL) in the first year.
Methods: An exploratory linear piecewise growth mixture modeling (PGMM) with one hypothetical dot (3 months since diagnosis, T1) was employed to identify different resilience patterns and growth in 289 patients with different cancer diagnoses at five assessment occasions (T0-T4). Logistic regression analysis was performed to select potential predictors and receiver operating characteristic (ROC) curve analysis was utilized to test PGMM's discriminative ability against 1-year QoL.
Prognostic communication between clinicians and parents in pediatric oncology is complex. However, no review has exclusively examined research on prognostic communication in pediatric oncology. In this review, we synthesize the evidence on prognostic communication in pediatric oncology and provide recommendations for future research.
View Article and Find Full Text PDFObjective: The application of advanced Cognitive Diagnosis Models (CDMs) in the Patient Reported Outcome (PRO) is limited due to its complex statistics. This study was designed to measure resilience using CDMs and its prediction of 6-month Quality of Life (QoL) in breast cancer.
Methods: A total of 492 patients were longitudinally enrolled from Be Resilient to Breast Cancer (BRBC) and administered with 10-item Resilience Scale Specific to Cancer (RS-SC-10) and Functional Assessment of Cancer Therapy-Breast (FACT-B).
Sleep disturbance is common among women with breast cancer and is associated with greater symptom distress and poorer outcomes. Yet, for the unique subgroup of young women with breast cancer (YWBC), there is limited information on sleep. To address the gap in our understanding of sleep health in YWBC, we explored their perspective on sleep quality, sleep changes over time, contributing factors, and any strategies used to promote sleep.
View Article and Find Full Text PDFPurpose: To explore the experience of oncology nurses during the first year of the COVID-19 pandemic.
Participants & Setting: 21 RNs, advanced practice RNs, and physician associates from inpatient and ambulatory care settings at a comprehensive cancer center in the northeastern United States.
Methodologic Approach: A qualitative study using interpretive description was conducted through semistructured interviews.
Objective: The aims of this study were to explore the experience of retirement-age nurses and identify decision-making factors and innovations to enhance retention.
Background: A national shortage of nurses has created challenges to preserving quality patient care and level of nursing competency and managing turnover costs.
Methods: A qualitative study using focus groups was conducted of nurses 55 years or older who were working or recently retired.
Young women with breast cancer (YWBC) report physical and psychological symptom distress after therapy but little is known about their sleep health. The purpose of this study was to identify sociodemographic, clinical, and psychosocial factors associated with sleep health and assess the potential role of appraisal of illness and coping on sleep health. An adapted cognitive appraisal and coping conceptual framework guided the study.
View Article and Find Full Text PDFBackground: Resilience is important in cancer survivorship and has great potential to predict long-term quality of life (QoL) in breast cancer. The study was designed to develop a new prediction model to estimate pretest probability (PTP) of 1-year decreased QoL combing Resilience Index (RI) and conventional risk factors.
Methods: RI was extracted from 10-item Resilience Scale Specific to Cancer (RS-SC-10) based on the Principal Component Analysis (PCA).
Background: Heart failure affects approximately 6.2 million adults in the United States and has an estimated national cost of $30.7 billion annually.
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