Developing the Weaving Healthy Families Program to Promote Wellness and Prevent Substance Abuse and Violence: Approach, Adaptation, and Implementation.

Family prevention programs that enhance mental health, wellness, and resilience-while simultaneously addressing violence and alcohol and other drug (AOD) abuse-among Indigenous families are scarce. This gap in culturally grounded and community-based programs creates a critical need to develop and evaluate the efficacy of such prevention programs. This article fills this gap, with the purpose of describing the structure and content of the Weaving Healthy Families (WHF) program, a culturally grounded and community-based program aimed at preventing violence and AOD use while promoting mental health, resilience, and wellness in Indigenous families.

"You Can Get Away with Anything Here… No Justice at All"- Sexual Violence Against U.S. Indigenous Females and Its Consequences.

Sexual violence against Indigenous women has long been used as a tool of colonial violence and conquest. As a contemporary form of historical oppression that may drive associated health and mental health inequities, Indigenous women in the United States experience sexual violence at greater levels than the general population and at and twice the rate of Indigenous men. We use the Indigenous framework of historical oppression, resilience, and transcendence (FHORT) to understand Indigenous women's experiences of sexual violence and how it differentiates across ecological outcomes related to health and wellness.

"When You Come Together and Do Everything, It'll be Better for Everybody": Exploring Gender Relations Among Two Southeastern Native American Tribes.

Prior to the imposition of patriarchal colonial norms, Native American (NA) gender relations were characterized as complementary and egalitarian; however, little research has explored gender relations within NA communities today. This study used a community-based critical ethnography to explore contemporary NA gender relations with a purposive sample of 208 individuals from the "Coastal Tribe" and 228 participants from the "Inland Tribe." After participant observation, interviews, and focus groups were conducted, a collaborative approach to reconstructive analysis was used to identify themes in the data.

'A learning experience': Disciplinary and parenting practices among Native American families.

Research indicates that effective disciplinary practices, such as offering praise and teaching acceptable versus non-acceptable behaviour, can act as protective factors against the social and behavioural health disparities experienced by Native Americans (NA). The purpose of this critical ethnographic study ( = 436 qualitative elder, adult, youth and professional participants) was to use the Framework of Historical Oppression, Resilience, and Transcendence (FHORT) to qualitatively examine participants' reported experiences of disciplinary practices. Thematic analysis of qualitative results indicated several approaches to disciplining children, which included the following themes: (a) Establishing Structure and Boundaries; (b) Taking Away Privileges and Rewarding Good Behavior; and (c) Teaching Right from Wrong.

"I Have to Watch Them Closely": Native American Parenting Practice and Philosophies.

One of many ways that Native American (NA) families demonstrate resilience is by parenting children in some of the most adverse contexts in U.S. society.

"A Dad Can Get the Money and the Mom Stays at Home": Patriarchal Gender Role Attitudes, Intimate Partner Violence, Historical Oppression, and Resilience Among Indigenous Peoples.

Research has shown that gender role attitudes influence a number of health-related outcomes, including intimate partner violence (IPV). Yet the gender role attitudes of Indigenous peoples - a population that experiences persistent health and violence disparities - have received scant scholarly attention. Using the Framework of Historical Oppression, Resilience, and Transcendence (FHORT), the purpose of this mixed methodology was to qualitatively explore U.

"She's the Center of My Life, the One That Keeps My Heart Open": Roles and Expectations of Native American Women.

Historically, Native American (NA) mothers have proven essential to the survival of their families and communities, yet scant research has examined their roles today. Current gender roles in NA communities are influenced by historical oppression (both historic and contemporary forms) that acted to reverse matrilineal gender norms in favor of patriarchy. The present study sought to explore norms and expectations for women among two NA tribes located in the southeastern region of the United States.

Biweekly Cetuximab Plus FOLFOX6 as First-Line Therapy in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The CEBIFOX Trial.

Background: The multicenter, single-arm, phase II study CEBIFOX evaluated the efficacy of a biweekly cetuximab administration in combination with FOLFOX6 as first-line therapy in KRAS (exon 2) wild-type (wt) metastatic colorectal cancer (mCRC).

Patients And Methods: Patients received FOLFOX6 with cetuximab (500 mg/m) every second week. Primary endpoint was objective response rate (ORR), among others secondary endpoints were safety, progression-free survival (PFS), overall survival (OS), and patient-reported outcome (PRO).

Hurricanes and Indigenous Families: Understanding connections with discrimination, social support, and violence on PTSD.

The purpose of this article is to use the culturally grounded Framework of Historical Oppression, Resilience, and Transcendence (FHORT) to examine (a) the experiences and impacts of hurricanes on Indigenous (i.e., Native American) family members in the Gulf Coast and (b) to identify how experiencing hurricanes and natural disasters, family and community support, adverse childhood experiences (ACE), discrimination and intimate partner violence (IPV) may be related to post-traumatic stress disorder (PTSD) among two Southeastern tribes.

Subspecialization in radiology and radiation oncology.

Practicing radiologists, radiation oncologists, and trainees were surveyed regarding the current state of subspecialization in practice and in training curricula. The authors present the results of these surveys, establish trends compared with previous survey data, and compare the plans of trainees with current postgraduate practice. Subspecialization is increasing in both radiology and radiation oncology.

Thrombosis of the muscular calf veins--reference to a syndrome which receives little attention.

Background: Thrombosis of the soleal and gastrocnemial veins seldom receive very much attention. It is thought that they are frequently the starting point for deep vein thrombosis of the lower extremity.

Patients And Methods: 125 patients with clinically suspected deep vein thrombosis of the leg were examined by means of duplex sonography and phlebography.

5-Fluorouracil, folinic acid, etoposide and cisplatin chemotherapy for locally advanced or metastatic carcinoma of the oesophagus.

38 patients with advanced oesophageal carcinoma were treated with intravenous (i.v.) folinic acid (300 mg/m2), 5-fluorouracil (500 mg/m2), etoposide (100 mg/m2), and cisplatin (30 mg/m2) (FLEP), on days 1, 2 and 3, every 22-28 days.

A pilot study of rapidly alternating epirubicin/dacarbazine and ifosfamide as first-line therapy for metastatic soft-tissue sarcoma in adults.

Currently, anthracyclines and ifosfamide are the most effective drugs for the treatment of disseminated soft-tissue sarcoma. We designed a treatment protocol of rapidly alternating epirubicin/dacarbazine and ifosfamide for previously untreated soft-tissue sarcoma, whereby 100 mg/m2 epirubicin was given on day 1, 500 mg/m2 dacarbazine was given on days 1 and 2, and 6,000 mg/m2 ifosfamide given via 24-h infusion was begun on day 15. The entire treatment cycle was scheduled to begin again on day 28 if the leukocyte count had reached 3.

Biochemical modulation of 5-fluorouracil by folinic acid or alpha-interferon with and without other cytostatic drugs in gastric, esophageal, and pancreatic cancer.

5-Fluorouracil (5-FU) is one of the important antineoplastic agents for the treatment of gastrointestinal cancers. The biochemical modulation of 5-FU by various drugs has brought about the two combinations of 5-FU/folinic acid (FA) and 5-FU/alpha-interferon (IFN), which have shown clinical activity in phase II and III trials, especially in colorectal cancer. The experience with both combinations in upper gastrointestinal cancers, however, is limited.

Interferon alpha-2b, 5-fluorouracil, and folinic acid combination therapy in advanced colorectal cancer: preliminary results of a phase I/II trial.

We conducted a phase I/II trial of 5-fluorouracil (5-FU)/folinic acid (FA) and alpha-2b interferon (IFN) in 43 previously untreated patients with measurable metastatic colorectal cancer. Patients had disease progression prior to therapy consistent of 5-FU 500 mg/m2 (level A) or 600 mg/m2 (level B) as starting dose administered as a 2-hour infusion, FA 200 mg/m2, and alpha-2b IFN 5MU/m2 subcutaneously. All drugs were given on days 1 to 5 and cycles were repeated after 3 to 4 weeks.

Phase II study of single-agent etoposide in patients with metastatic squamous-cell carcinoma of the esophagus.

A total of 26 evaluable patients presenting with advanced or metastatic squamous-cell carcinoma of the esophagus were entered in a phase II trial to assess the single-agent activity of etoposide. Etoposide was given at a dose of 200 mg/m2 on 3 consecutive days every 3 weeks. Five patients (19%) achieved a partial response and seven (27%) experienced stabilisation of their disease.

Preoperative chemotherapy in locally advanced and nonresectable gastric cancer: a phase II study with etoposide, doxorubicin, and cisplatin.

Thirty-four patients with locally advanced, nonresectable gastric cancer (staged by laparotomy) received etoposide, Adriamycin (doxorubicin; Adria Laboratories, Columbus, OH), and cisplatin (EAP). Thirty-three patients were evaluable for response and toxicity. Second-look surgery with removal of residual tumor by gastrectomy and lymphadenectomy was performed in case of complete/partial remission (CR/PR) after EAP.

Transplantable canine glioma model for use in experimental neuro-oncology.

The need for a large animal tumor model in experimental neuro-oncology led us to re-evaluate and to modify the transplantable canine glioma of Wodinsky and Walker. Successive passages of the original tumor brei were made in purebred beagles, from beagle to mongrel, and between various mongrel strains until an intracerebral injection of 0.1 cc on Days 1 to 3 of life produced a 93% incidence of tumor take in all breeds.

CT-angiographic correlation in Sturge-Weber syndrome.

Sturge-Weber syndrome in its classic form can be easily diagnosed by CT. However, in the absence of the typical gyral calcification, the diagnosis can be missed on CT. Identification of the intracranial angiomatosis and the associated thrombosis, and thus the diagnosis, require angiography.

Computed tomographic findings in cerebral sinus and venous thrombosis.

Cerebral sinus and venous thrombosis were diagnosed by computed tomography (CT) and subsequently confirmed by other studies in eleven patients. CT revealed normal or small ventricles, hemorrhages, low-density areas, and increased density of dural sinuses and tentorium. CT in combination with appropriate angiographic studies is necessary for diagnosis and confirmation of sinus and venous thrombosis.

[Brain atrophy in chronic alcoholism. Clinical and computer tomographic study].

Fifty chronic alcoholics (37 men and 13 women, ages 26--55, mean age 39.9 years) with different clinical syndromes (alcoholic psychosis, alcoholic encephalopathies) were studied by computerized cranial tomography. Cerebral atrophy was detected in 96% of all cases.