Toxic effect of insecticide dimethoate applied to 400 rats for two years in concentrations of 2 to 200 mg/kg fodder was investigated. During the last six months of observation the toxic influence of the larger doses of this preparation was manifested by a higher mortality of the animals. Neither disadvantageous influence upon the maturation of each individual haemopoietic series, nor action inducing pathologic proliferation in the haemopoietic system of rats were found.
View Article and Find Full Text PDFThe results of a chronic 2-years experiment of thiram on Wistar-rats are given. On the basis of clinical, biochemical and pathomorphological investigations a Noel of 5 mg/kg bw were proposed.
View Article and Find Full Text PDFThirty-eight children were evaluated for interstitial pneumonia by open lung biopsy. In most instances the patients were immunosuppressed as a result of cancer chemotherapy and irradiation. Pneumocystis carinii infection was the most common cause of pneumonitis (60.
View Article and Find Full Text PDFA review of analytical methods for determination of dithiocarbamate residues by carbon disulphide evaluation method was made. On basis of KEPPEL method the colorimetric step was modified. For this purpose the reaction of hydrogen sulphide with p-aminodimethylaniline in the presence of ferric and zinc ions to form methylene blue was applied.
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