[The effect of low-energy laser radiation and interferon to delay chemical carcinogenesis].

A significant delay in benz(A)pyrene-induced tumorigenesis was obtained following three series of parenteral injection of xenogenic leukocytic interferon alternating with irradiation at 3-4 day intervals. Radiation was delivered from a red low-energy laser through a puncture in the peritoneal wall of the spleen. When each of said procedures was performed separately similar effects were recorded but the changes were not significant.

High-porosity activated carbons for bilirubin removal.

The aim of this study was to clarify the relationship between the extent of activation of synthetic granula and fibrous carbons and the adsorption of bilirubin from protein solutions. The total pore volumes of granular carbons START, SCN and fibrous activated carbons ACFM were 0.9-2.

Enterosorption in oncotherapy.

Patients with lymphogranulomatosis undergoing radiotherapy according to the radical scheme were treated with fibrous carbon enterosorbent VESTA in tablets for 14 days (group I, 23 patients) from the moment of leukopenia development (lower then 2.2 x 10(9)/l) or were traditionally treated using parenteral administration of hemostimulants, hemosubstitutes and detoxicants (group II, 23 patients). After 14 days leukopenia was cured in 18 patients of group I (78%) and in 11 patients of group II (48%), with an average number of leukocytes in the patients of groups I and II growing by 2 and 1.

[The systemic and regional changes in the modelling of a massive pulmonary artery embolism].

In anesthetized dogs with natural breathing, embolisation of pulmonary arterial bed increased systolic pressure in the right ventricle of the heart up to 60.0-113.0 mm Hg.

[The prevention and treatment of periodontal diseases in bronchial asthma patients undergoing a course of treatment in a hypoxic barochamber].

The authors analyze the effects of hypoxia on clinical status and function of periodontal tissues in 71 asthmatics treated in a hypoxic chamber. Functional diagnosis methods were used in the study. The findings formed the basis for recommendations on the prevention and therapy of the shifts developing in the periodontium.

Comparative evaluation of the structure and properties of certain granulated and fibrous activated carboniferous sorbents.

This paper presents the results of the comparative evaluation of the structure and sorption properties of fibrous (AYBM- -MH) and granulated (CKH-IK) carboniferous sorbents. The structure of sorbents was investigated using scanning electron microscopy (SEM) and electron paramagnetic resonance (EPR), while the sorption properties were studied through application of adsorption-desorption of markers (medinal, creatinine, uric acid, vitamin B12). Carbon fiber sorbents have been found to possess more favorable characteristics of the sorptive capacity and a better porous structure.

[Mechanism of stimulation of duodenal contractions by the greater splanchnic nerve].

The mechanism of duodenal motor activity stimulation has been studied in dogs during irritation of the chest area of the greater splanchnic nerve. It has been established that a stimulating effect of the splanchnic nerve was not removed either by bilateral vagotomy or by separate and combined injections of bretylium tosylate and benzohexamethonium, but was removed by the blockade of M-serotoninergic receptors of the autonomic ganglia with atropine or by the blockade of D-serotoninergic receptors of the smooth muscles with promethazine hydrochloride. The data obtained demonstrate the presence of noncholinergic and nonadrenergic fibers in the chest area of the greater splanchnic nerve, having a potent stimulating effect on duodenal contractions.

[Mechanism of stimulation of the motor activity of the stomach by the greater splanchnic nerve].

The activating effect of the splanchnic nerve on motor activity of the gastro-intestinal tract could not be eliminated either with bilateral vagotomy or separate or joint administration of ornid and benzohexonium, but could be well prevented with atropin blockade of the vegetative ganglia M-serotoninergic receptors as well as diprazin blockade of the smooth muscle D-serotoninergic receptors. The data obtained reveal non-cholinergic and non-adrenergic fibers in the thoracic portion of the major splanchnic nerve which exert obvious activating effect on the stomach contractile function, serotonin being their transmitter.

[Comparative study of the action of acetylcholine on the transmembrane potentials of the contractile myocardial cells of the ventricles in adult and newborn guinea pigs].

The transmembrane potentials of the contractile myocardium cells of intact heart and their response to acetylcholine were studied in adult and newborn guinea pigs by means of "swimming microelectrodes". High concentration of acetylcholine only slightly reduces the overshoot without causing changes in other parameters of the transmembrane potentials in adult animals whereas in newborn animals acetylcholine induces hyperpolarization of membrane of the contractile myocardium cells, increases the overshoot and the amplitude of the AP. In adult guinea pigs, acetylcholine prevents irreversible fibrillation whereas in newborn animals acetylcholine prevents spontaneous defibrillation.