The Finnish evidence-based guideline for open-angle glaucoma.

In most patients, chronic open-angle glaucoma is a slowly progressive disease. Eyes with very high intraocular pressure (IOP > 30 mmHg) represent an exception to this and should be treated and followed extremely intensively. As lowering IOP is, so far, the only means of treating glaucoma, the majority of research reports deal with the IOP-lowering effect of the treatment.

Compression forces of haptics of selected posterior chamber lenses.

Purpose: To compare the compressive forces of the haptics of different intraocular lens (IOL) models and analyze the observed differences.

Setting: Central Hospital of Central Finland and University of Jyväskylä, Jyväskylä, Finland.

Methods: The haptics of 28 IOL models were compressed to a diameter of 9.

Ophthalmic manifestations of epidemic nephropathy.

An ophthalmic examination was performed on 29 epidemic nephropathy patients consequently treated in the Central Hospital of Central Finland during the acute phase of the disease. Twenty-six of those patients were reexamined after an interval of one month. In the acute phase of the disease pathological ophthalmic changes were found in 15 cases (52%).

The dexamethasone provocative test: a predictive tool for glaucoma?

A retrospective follow-up study of 134 patients (84 women and 50 men) tested for their responsiveness to topically administered corticosteroids was carried out. Of the 134 patients tested, 34 (25.4%) had a high response (IOP rise greater than or equal to 16 mmHg), 66 (49.

Effect of spectacle use and accommodation on myopic progression: final results of a three-year randomised clinical trial among schoolchildren.

Two hundred and forty mildly myopic schoolchildren aged 9-11 years were randomly allocated to three treatment groups and the progression of myopia was followed-up for three years. The treatment groups were: (1) minus lenses with full correction for continuous use (the reference group), (2) minus lenses with full correction to be used for distant vision only, and (3) bifocal lenses with +1.75 D addition.

Intraocular pressure in exfoliation syndrome.

A retrospective follow-up study of 206 eyes with exfoliation in 164 patients was carried out. At the time exfoliation (EX) was initially diagnosed, there were 97 patients with unilateral and 42 patients (84 eyes) with bilateral exfoliation. In 25 patients the exfoliation was connected with hypertension or glaucoma in the fellow eye.

A double-masked study of timolol and pilocarpine combined.

In a double-masked, randomized, multicenter study, 25 patients received timolol 0.5%-pilocarpine 2% twice a day, 25 received timolol 0.5%-pilocarpine 4% twice a day, and 25 received pilocarpine 4% four times a day.

Combined trabeculectomy and cataract operation. A follow-up study.

In a study of 94 combined cataract and trabeculectomy operations performed for 59 open angle simplex and 35 capsular glaucoma with coexisting cataract, followed up for 1 to 9 years, the overall control of intraocular pressure (less than or equal to 21 mm Hg) without therapy was achieved in 61 eyes (65%). The average follow-up time was 3.4 years.

Timolol treatment of chronic open-angle glaucoma and ocular hypertension. A 2.5-year multicenter study.

Maintenance effect of topical timolol was investigated for 2 years in a group of 125 glaucomatous and ocular hypertensive patients (231 eyes) who had been successfully treated with timolol alone during a 6-month period preceding this trial. Intraocular pressure (IOP) was controlled with timolol alone in 135 of 183 eyes (74%) that completed the study. At the end of the trial 142 eyes (78%) showed an IOP of less than 22 mmHg.

The IOP-lowering effect of timolol in simple and capsular glaucoma. A multicenter study in Finland.

Timolol maleate eye drops (0.25% and 0.5%) were used alone or in combined treatment in 220 patients with simple or capsular glaucoma.

Late complications of 7-0 polyglycolic (Dexon) sutures in cataract surgery.

The late complications of corneo-scleral wound healing after the 15th postoperative day were recorded in 108 routine adult cataract operations using 7-0 polyglycolic acid (Dexon) sutures and compared with 80 routine adult cataract operations using 9-0 monofilament nylon (9-10 Ethilon Nylon) sutures. In 37 eyes of the 7-0 Dexon group filtrating blebs, gaping of the corneoscleral wound, anterior chamber collapse, or decrease in the intraocular pressure were observed compared with one filtrating bleb in the 9-0 nylon group. The majority of late complications occurred 22 to 42 days after surgery.

Congenital defects in a cohort followed for seven years.

A geographically limited cohort of Finnish children was followed from birth for seven years, and all congenital abnormalities were recorded and classified and special attention was given to the cumulative detection rate, and the time of detection of various defects. Of 3674 pregnancies 135 babies with or without defects were stillborn or died during the neonatal period. The remaining 3539 were followed up to seven years, when the percentage follow-up was 81.

Definition of congenital malformations and detection of associations with maternal factors.

Data collected from a cohort of 2913 pregnancies were analyzed to determine whether the varying definitions of congenital malformations influence the statistical result in the search for possible etiological factors. According to three different definitions of congenital malformations, three study groups were formed, i.e.

Screening for neonatal hearing disorders in the Province of Central Finland.

Screening for congenital hearing disorders in newborn infants has been carried out in the Province of Central Finland since 1967. In 1967-1971, a total of 23 children (12 boys and 11 girls) were found to have congenital hearind disorders. From this it can be calculated that 90 infants are born each year with congenital hearing disorders in Finland.