Synopsis of recent research by authors named "Klementina Fon Tacer"
- Klementina Fon Tacer's research focuses on the role of melanoma antigens (MAGEs) and their implications in various cancers, particularly pediatric medulloblastoma, where a significant proportion of group 3 tumors express MAGEs as potential prognostic markers.
- Her studies also investigate the molecular and genetic mechanisms underlying neuroendocrine functions, detailing the impact of MAGEL2 mutations in disorders like Prader-Willi syndrome, leading to altered neuropeptide production and hormonal regulation.
- Additionally, Tacer explores the broader roles of MAGE proteins in cellular stress responses, revealing how they contribute to stress tolerance in germ cells and their involvement in cancer-specific processes like mRNA alternative polyadenylation, highlighting their potential as therapeutic targets.
