Publications by authors named "Klaus Witt"

This article was migrated. The article was marked as recommended. Introduction In the general practice course at Copenhagen University, students are taught patient-centered consultations.

View Article and Find Full Text PDF

Users of online comprehensive two-dimensional liquid chromatography (LCxLC) frequently acknowledge that the mechanical instability of HPLC columns installed in these systems, particularly in the second dimension, is a significant impediment to its use. Such instability is not surprising given the strenuous operating environment to which these columns are subjected, including the large number (thousands per day) of fast and large pressure pulses resulting from interface valve switches (on the timescale of tens of milliseconds) associated with very fast second dimension separations. There appear to be no published reports of systematic studies of the relationship between second dimension column lifetime and any of these variables.

View Article and Find Full Text PDF

Introduction: It is vital that patients understand the language used in leaflets in medicine packages and in information for participation in medical research. The aim of the study was to determine the proportion of Danes with reading skills corresponding to 9-10 years of schooling who understand the language used by health-care professionals in materials targeted at laypeople.

Material And Methods: Based on a study of ordinary citizens' understanding of the language used in printed communication from Danish authorities we tested the words used in printed matters from the health-care system; specifically information forms and questionnaires from research protocols submitted to the local ethics committee.

View Article and Find Full Text PDF

The use of flow splitters between the two dimensions in online comprehensive two-dimensional (2D) liquid chromatography (LC × LC) has not received very much attention, in comparison with their use in 2D gas chromatography (GC × GC), where they are quite common. In principle, splitting the flow after the first dimension column and performing online LC × LC on this constant fraction of the first dimension effluent should allow the two dimensions to be optimized almost independently. When there is no flow splitting, any change in the first-dimension flow rate has an immediate impact on the second dimension.

View Article and Find Full Text PDF

Background: Health care professionals worldwide attend courses and workshops to learn evidence-based medicine (EBM), but evidence regarding the impact of these educational interventions is conflicting and of low methodologic quality and lacks generalizability. Furthermore, little is known about determinants of success. We sought to measure the effect of EBM short courses and workshops on knowledge and to identify course and learner characteristics associated with knowledge acquisition.

View Article and Find Full Text PDF

Introduction of a sample into the separation column (microchip channel) in capillary zone electrophoresis (microchip electrophoresis) will cause a disturbance in the originally uniform composition of the background electrolyte. The disturbance, a system zone, can move in some electrolyte systems along the separation channel and, on reaching the position of the detector, cause a system peak. As shown by the linear theory of electromigration based on linearized continuity equations formulated in matrix form, the mobility of the system zone--the system eigenmobility--can be obtained as the eigenvalue of the matrix.

View Article and Find Full Text PDF

Background: Educational outreach visits, particularly when combined with social marketing, appear to be a promising approach to modifying health professional behaviour, especially prescribing. Results from previous studies have shown a varying effect.

Objective: The purpose of the study is to examine the effect of academic detailing as a method of implementing a clinical guideline in general practice.

View Article and Find Full Text PDF

Objectives: To describe where patients in Danish general practice get information about health and disease, particularly how patients prepare for a visit to their GP, with special reference to use of the lnternet.

Design: Structured interviews.

Setting: Four Danish general

Patients: 93 consecutive patients after visiting their GP.

View Article and Find Full Text PDF