Short and Long-Term Effectiveness of Ustekinumab in Patients with Crohn's Disease: Real-World Data from a German IBD Cohort.

Background and Aims: The IL-12/23 inhibitor ustekinumab (UST) opened up new treatment options for patients with Crohn's disease (CD). Due to the recent approval, real-world German data on long-term efficacy and safety are lacking. This study aimed to assess the clinical course of CD patients under UST therapy and to identify potential predictive markers.

Long-term results of endoscopic balloon dilatation of lower gastrointestinal tract strictures in Crohn's disease: a prospective study.

Aim: To examine the long-term results of endoscopic treatment in a prospective study conducted over a period of 10 years, 1997 to January 2007.

Methods: A total of 25 patients (20 female and five male: aged 18-75 years), with at least one symptom of stricture not passable with the standard colonoscope and with a confirmed scarred Crohn's stricture of the lower gastrointestinal tract, were included in the study. The main symptom was abdominal pain.

[Endoscopic clipping of a gastric perforation after GIST resection].

Background: The application of endoscopic clips in the therapy of bowel or stomach perforations has been reported in few cases only.

Case Report: In a 43-year-old woman, endoscopic resection of a submucosal gastric tumor sized 1.2 cm, histologically proven to be a gastrointestinal stromal tumor (GIST), was complicated by bleeding and a small perforation.