Restoring Tactile sensations via neural interfaces for real-time force-and-slippage closed-loop control of bionic hands.

Despite previous studies on the restoration of tactile sensation on the fingers and the hand, there are no examples of use of the routed sensory information to finely control the prosthesis hand in complex grasp and manipulation tasks. Here it is shown that force and slippage sensations can be elicited in an amputee subject by means of biologically-inspired slippage detection and encoding algorithms, supported by a stick-slip model of the performed grasp. A combination of cuff and intraneural electrodes was implanted for eleven weeks in a young woman with hand amputation, and was shown to provide close-to-natural force and slippage sensations, paramount for significantly improving the subject's manipulative skills with the prosthesis.

Prolonged Corrosion Stability of a Microchip Sensor Implant during In Vivo Exposure.

A microelectronic biosensor was subjected to exposure by implanting it in the vicinity of (Trapezius muscle) from cattle. The implant is intended for the continuous monitoring of glucose levels, and the study aimed at evaluating the biostability of exposed semiconductor surfaces. The sensor chip was a microelectromechanical system (MEMS) prepared using 0.

Accurate and representative decoding of the neural drive to muscles in humans with multi-channel intramuscular thin-film electrodes.

Intramuscular electrodes developed over the past 80 years can record the concurrent activity of only a few motor units active during a muscle contraction. We designed, produced and tested a novel multi-channel intramuscular wire electrode that allows in vivo concurrent recordings of a substantially greater number of motor units than with conventional methods. The electrode has been extensively tested in deep and superficial human muscles.

Total mesorectal excision--does the choice of dissection technique have an impact on pelvic autonomic nerve preservation?

Background: The aim of this experimental study was to assess the quality of pelvic autonomic nerve preservation of different dissection techniques.

Material And Methods: Twelve pigs underwent low anterior rectal resection (LARR) with scissors, ultracision, monopolar diathermy, and waterjet, each in three animals. Assessment of pelvic autonomic nerve preservation was carried out by stimulation of the pelvic splanchnic nerves under electromyography of the internal anal sphincter (IAS).

3D hybrid electrode structure as implantable interface for a vestibular neural prosthesis in humans.

Implantable interfaces are essential components of vestibular neural prostheses. They interface the biological system with electrical stimulation that is used to restore transfer of vestibular information. Regarding the anatomical situation special 3D structures are required.

Total mesorectal excision with intraoperative assessment of internal anal sphincter innervation provides new insights into neurogenic incontinence.

Background: The aim of this prospective study was to assess internal anal sphincter (IAS) innervation in patients undergoing total mesorectal excision (TME) by intraoperative neuromonitoring (IONM).

Study Design: Fourteen patients underwent TME. IONM was carried out through pelvic splanchnic nerve stimulation under continuous electromyography of the IAS.

An implantable microactuated intrafascicular electrode for peripheral nerves.

Important advancements have been recently achieved in the field of neural interfaces to restore lost sensory and motor functions. The aim of this letter was to develop an innovative approach to increase the selectivity and the lifetime of polyimide-based intrafascicular electrodes. The main idea was to obtain a neural interface that is able to restore a good signal quality by improving the electrical connection between the active sites and the surrounding axons.

On the use of longitudinal intrafascicular peripheral interfaces for the control of cybernetic hand prostheses in amputees.

Significant strides have been recently made to develop highly sensorized cybernetic prostheses aimed at restoring sensorimotor limb functions to those who have lost them because of a traumatic event (amputation). In these cases, one of the main goals is to create a bidirectional link between the artificial devices (e.g.

Mental rotation and rotational invariance in the Rhesus monkey (Macaca mulatta).

The mode of visual information processing during visuospatial tasks differs across species and is supposed to depend on evolutionary and ecological factors. Humans show reaction times that increase with angular disparity when tested in mental rotation tasks. Pigeons show a time-independent rotational invariance that possibly evolved in response to the horizontal reference plane birds perceive while flying.