Semipermeable glove membranes--effects on skin barrier repair following SLS irritation.

Background: Transepidermal water flux is the regulatory signal for barrier regeneration.

Objective: In this study, we evaluated the impact of glove membranes, which provide a partial barrier and different water loss rates, on barrier recovery after standardized irritation with sodium lauryl sulfate (SLS).

Methods: Twenty-five healthy volunteers were irritated for 24 hr with SLS 1%.