Publications by authors named "Klaudia Spitzer"
Article Synopsis
- Researchers studied spontaneous synchronous population activity (SPA) in cortical slices from epileptic patients using electrophysiological methods and two-photon imaging to explore its network mechanisms.
- They maintained brain tissue in a special dual perfusion chamber and recorded SPA while identifying active regions using 24-channel microelectrodes.
- The combination of high-resolution imaging and electrophysiology allowed for detailed analysis of neuron interactions and their anatomy, providing insights into the human neocortex's structural and functional properties.
Rationale: Recent evidence suggests that in addition to controlling emotional behavior in general, endocannabinoid signaling is engaged in shaping behavioral responses to challenges. This important function of endocannabinoids is still poorly understood.
Objectives: Here we investigated the impact of blockade of fatty acid amide hydrolase (FAAH), the degrading enzyme of anandamide on behavioral responses induced by challenges of different intensity.