Spinal deformities and lung function in adults with osteogenesis imperfecta.

Introduction: There are no larger studies of adults with osteogenesis imperfecta (OI), focusing on the impact of spinal cord deformities on lung function assessment.

Objectives: To assess prevalence and severity of spinal deformities and lung function in an adult population with OI and to explore whether compromise of lung function correlated with deformities of the spine.

Methods: Ninety-two adults with OI had radiographs of the spine, 75 underwent spirometry.