No change in health behavior, BMI or self-rated health after a psychosocial cancer rehabilitation: Results of a randomized trial.

Introduction: The aim of cancer rehabilitation is to enable patients to attain and maintain optimal physical, psychological and social functioning. We evaluated the effect on health behavior, BMI and self-rated health of a residential psychosocial rehabilitation course for cancer patients.

Material And Methods: Patients with a primary cancer of the breast, prostate, colon or rectum were randomized to either a six-day multi-focus psychosocial residential rehabilitation intervention that included lectures, discussions and peer group discussions on issues related to treatment and life with cancer or to usual care.

Maternal intake of fish oil but not of linseed oil reduces the antibody response in neonatal mice.

Dietary levels of n-3 PUFA are believed to influence the immune system. The importance of the source of n-3 PUFA is debated. This study addressed how the content and source of n-3 PUFA in the maternal diet influenced tissue FA composition and the immune response to ovalbumin (OVA) in mice pups.

Cost analysis of establishing dialysis facilities for the treatment of chronic renal failure in Greenland.

Objectives: At present there are no facilities offering treatment for chronic renal failure with dialysis in Greenland. Patients in need of treatment must go to Denmark. It has been proposed that treatment facilities should be established at Dronning Ingrids Hospital in Nuuk, Greenland.

Automatic epileptic seizure onset detection using matching pursuit: a case study.

An automatic alarm system for detecting epileptic seizure onsets could be of great assistance to patients and medical staff. A novel approach is proposed using the Matching Pursuit algorithm as a feature extractor combined with the Support Vector Machine (SVM) as a classifier for this purpose. The combination of Matching Pursuit and SVM for automatic seizure detection has never been tested before, making this a pilot study.

Automatic seizure detection: going from sEEG to iEEG.

Several different algorithms have been proposed for automatic detection of epileptic seizure based on both scalp and intracranial electroencephalography (sEEG and iEEG). Which modality that renders the best result is hard to assess though. From 16 patients with focal epilepsy, at least 24 hours of ictal and non-ictal iEEG were obtained.

Impact of symptom burden on health related quality of life of cancer survivors in a Danish cancer rehabilitation program: A longitudinal study.

Introduction: Little research has been conducted on the effect of self-reported rating of symptom severity on quality of life (QoL) among cancer survivors. The aim of the study was to examine the prevalence of symptoms and whether information about self-reported symptom severity adds value to QoL measurements.

Material And Methods: A questionnaire including the EORTC QLQ-C30 and an empirically derived symptom check-list was completed by 2 486 cancer survivors participating in a rehabilitation program at baseline and at 1, 6 and 12 months' follow-up.

Cancer incidence among male Danish nurses, 1980-2003.

Background: The cancer risk of female nurses has been examined in several studies, but none has addressed the risk of male nurses, although they may be exposed to the same carcinogens as female nurses. In this register-based cohort study, we explored cancer incidence among male Danish nurses.

Methods: We identified 3369 male nurses from the files of the Danish Nurses Association and followed them up from 1980 to 2003 in the Danish Cancer Registry.

[How does it affect the brain when the vision is changed?].

Until quite recently, only the young brain was thought to be capable of adaptation. It is now known that also the aging brain is plastic and may be influenced by stimulation and pharmacological intervention. Future demographic changes will bring an increase in the incidence of age-related diseases.

Differences in cortical and pituitary activity in response to hypoglycaemia and cognitive testing in healthy men with different basal activity of the renin-angiotensin system.

Introduction: High renin-angiotensin system (RAS) activity has been associated with a high risk of severe hypoglycaemia in patients with type 1 diabetes and with cognitive deterioration during experimental hypoglycaemia in healthy subjects. The aim of this study was to describe possible differences in cerebral activity during hypoglycaemia and cognitive testing in two groups of healthy men with different basal RAS activity.

Methods: Ten healthy men with high RAS activity and 10 with low activity underwent six oxygen-15-labelled water positron emission tomography scans: twice during normoglycaemia, twice during insulin-induced hypoglycaemia and twice during post-hypoglycaemia.

Does the number of choice sets matter? Results from a web survey applying a discrete choice experiment.

Optimising the design of discrete choice experiments (DCE) involves maximising not only the statistical efficiency, but also how the nature and complexity of the experiment itself affects model parameters and variance. The present paper contributes by investigating the impact of the number of DCE choice sets presented to each respondent on response rate, self-reported choice certainty, perceived choice difficulty, willingness-to-pay (WTP) estimates, and response variance. A sample of 1053 respondents was exposed to 5, 9 or 17 choice sets in a DCE eliciting preferences for dental services.

Intraoperative hyperventilation vs remifentanil during electrocorticography for epilepsy surgery - a case report.

Background: Traditionally, intraoperative intracranial electroen-cephalography-recordings are limited to the detection of the irritative zone defined by interictal spikes. However, seizure patterns revealing the seizure onset zone are thought to give better localizing information, but are impractical due to the waiting time for spontaneous seizures. Therefore, provocation by seizure precipitants may be used with the precaution that spontaneous and provoked seizures may not be identical.

CD4(+) T-cell activation is differentially modulated by bacteria-primed dendritic cells, but is generally down-regulated by n-3 polyunsaturated fatty acids.

Appropriate activation of CD4(+) T cells is fundamental for efficient initiation and progression of acquired immune responses. Here, we showed that CD4(+) T-cell activation is dependent on changes in membrane n-3 polyunsaturated fatty acids (PUFAs) and is dynamically regulated by the type of signals provided by dendritic cells (DCs). Upon interaction with DCs primed by different concentrations and species of gut bacteria, CD4(+) T cells were activated according to the type of DC stimulus.

Cancer incidence among large cohort of female Danish registered nurses.

Background: Nurses are potentially exposed to carcinogens in their working environment. We investigated the risks for 21 types of cancers in Danish nurses.

Methods: We identified 92 140 female nurses from the computerized files of the Danish Nurses' Association.

Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity.

Introduction: High basal renin-angiotensin system (RAS) activity is associated with increased risk of severe hypoglycaemia in type 1 diabetes. We tested whether this might be explained by more pronounced cognitive dysfunction during hypoglycaemia in patients with high RAS activity than in patients with low RAS activity.

Materials And Methods: Nine patients with type 1 diabetes and high and nine with low RAS activity were subjected to hypoglycaemia and euglycaemia in a cross-over study using an intravenous insulin infusion protocol.

Coherence in consciousness: paralimbic gamma synchrony of self-reference links conscious experiences.

A coherent and meaningful percept of the world is essential for human nature. Consequently, much speculation has focused on how this is achieved in the brain. It is thought that all conscious experiences have reference to the self.

Association between regional cerebral blood flow during hypoglycemia and genetic and phenotypic traits of the renin-angiotensin system.

The risk of severe hypoglycemia in patients with type I diabetes and high basal activity in the renin-angiotensin system (RAS) is significantly higher than in patients with low basal RAS activity. In healthy men, we tested the hypothesis that differences in spontaneous RAS activity are associated with differences in cerebral activity responses during mild hypoglycemia. A total of 10 healthy men with high and 10 with low spontaneous RAS activity were selected.

Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.

Fish oil (FO) is considered antiinflammatory, but evidence regarding its effect on human cytokine production is conflicting. High linoleic acid (LA) intake may impair any effects of FO. The aim of this study was to investigate how FO combined with high or low LA intake affected ex vivo cytokine production from cultures of whole blood, peripheral blood mononuclear cells (PBMC), and monocytes in healthy men.

The protective mechanisms induced by a fish rhabdovirus DNA vaccine depend on temperature.

DNA vaccines encoding the viral glycoproteins of viral haemorrhagic septicaemia virus (VHSV) and infectious haematopoietic necrosis virus (IHNV) have proved highly efficient in rainbow trout (Oncorhynchus mykiss) under experimental conditions. Non-specific as well as specific immune mechanisms seem to be activated. Temperature is an important external parameter affecting the immune response in fish.

Whole-blood culture is a valid low-cost method to measure monocytic cytokines - a comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes.

Whole-blood and peripheral blood mononuclear cell (PBMC) cultures are used as non-validated surrogate measures of monocytic cytokine production. The aim of this investigation was to compare ex vivo cytokine production from human whole-blood and PBMC with that from isolated monocytes. We also assessed the intra- and inter-individual variation in cytokine production.

Social inequality and incidence of and survival from malignant melanoma in a population-based study in Denmark, 1994-2003.

The incidence of cutaneous malignant melanoma has increased more than that of any other cancer in most white populations during the past few decades. We investigated the effects of socioeconomic, demographic and health-related indicators on the incidence of and survival from malignant melanoma in 1994-2003 in Denmark using information from nationwide registries. The analyses were based on data on 6914 patients with malignant melanoma in a cohort of 3.

Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans.

Introduction: In type 1 diabetes increased risk of severe hypoglycaemia is associated with high angiotensin-converting enzyme (ACE) activity. We tested in healthy humans the hypothesis that this association is explained by the reduced ability of subjects with high ACE activity to maintain normal cognitive function during hypoglycaemia.

Methods: Sixteen healthy volunteers selected by either particularly high or low serum ACE activity were subjected to hypoglycaemia (plasma glucose 2.

Remifentanil-induced spike activity as a diagnostic tool in epilepsy surgery.

Objectives: To assess the value of remifentanil in intraoperative evaluation of spike activity in patients undergoing surgery for mesial temporal lobe epilepsy (MTLE).

Materials And Methods: Twenty-five patients undergoing temporal lobectomy for medically intractable MTLE were enrolled in the study. Electrocorticography (ECoG) recordings were performed on the intraventricular hippocampus and from the anterior inferior temporal and lateral neocortex before and after a 300 microg intravenous bolus of remifentanil.

Preference heterogeneity and choice of cardiac rehabilitation program: results from a discrete choice experiment.

This paper focuses on the elicitation of patients' preferences for cardiac rehabilitation activities from a discrete choice experiment using a mixed model. We observed a high level of preference heterogeneity among patients for all the five cardiac rehabilitation activities--even when age and smoking status were taken into account. The random parameter model provided additional policy relevant information as well as a better fit to the data than did the standard logit model.