[A modified technique for transsubmucosal maxilloethmoid sinus surgery through the inferior turbinate--transsubmucosal sinus surgery through the inferior turbinate].

In 1993, in the Journal of the Oto-Rhino-Laryngological Society of Japan, the authors published an endoscopic endonasal approach to surgery for chronic sinusitis, performing a transsubmucosal maxillectomy, ethmoidectomy and sphenoidectomy through the inferior turbinate, which the authors tentatively termed "swinging of the nasolacrimal duct and inferior turbinate." With the original technique, some bony structure was left partially exposed during resection of the mucosa in some patients, who suffered from postoperative crust formation. This technique thus required improvement.

A case of calcific retropharyngeal tendinitis: the significance of an early diagnosis.

The clinical presentation of calcific retropharyngeal tendinitis, a rare entity, can mimic more serious disorders. We describe the case of a 35-year-old man who was referred to us for evaluation of a suspected retropharyngeal abscess. At presentation, the patient reported severe cervical pain and stiffness.

Marrow-middle ear connections: a potential cause of otogenic meningitis.

Hypothesis: We hypothesize that the connections between the hematopoietic bone marrow and middle ear is a potential cause of childhood otogenic meningitis.

Background: Although it is known that there is a causal relationship between otitis media and bacterial meningitis, the relationship has never been satisfactorily established. Human fetal and infant temporal bones prepared for light microscopic evaluation revealed direct connections between the hematopoietic bone marrow and middle ear.

Cochlear changes in presbycusis with tinnitus.

Objectives: The pathophysiology of tinnitus is obscure and its treatment is therefore elusive. Significant progress in this field can only be achieved by determining the mechanisms of tinnitus generation, and thus, histopathologic findings of the cochlea in presbycusis with tinnitus become crucial. We revealed the histopathologic findings of the cochlea in subjects with presbycusis and tinnitus.

Pathologic correlations of otologic symptoms in acute lymphocytic leukemia.

Objectives: To assess the clinicopathologic correlations of otologic complaints in patients with acute lymphocytic leukemia.

Design: Otologic complaints and histologic findings were evaluated in 25 temporal bones of 13 acute lymphocytic leukemia patients.

Results: Nine patients had a history of otologic complaints, including hearing loss, otalgia, otorrhea, and vertigo in 5, 3, 3, and 2 patients, respectively.

[Adjuvant chemotherapy with S-1 for head and neck carcinoma].

Combined chemotherapy is considered essential for further improvement of the cure rate of head and neck carcinoma. Chemotherapy in cases of head and neck carcinoma is administered with one of two objectives: as adjuvant therapy to increase the survival rate after radical treatment in the early stage of the disease, and to prolong the survival rate in cases with advanced or recurrent carcinoma. There is, however, no clear answer to the question of how these objectives can be accomplished.

Extramedullary plasmacytoma of the larynx: a case report from Japan.

Laryngeal plasmacytoma is rare in Japan; to the best of our knowledge, only 8 other cases have been previously reported. We report a new case of extramedullary plasmacytoma of the larynx in a 76-year-old Japanese woman. Immunohistochemical investigation revealed that her disease had not progressed to multiple myeloma.

Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.

Background: Allergen-specific immunotherapy, although not a cure, remains the only treatment available that can alter the natural course of an allergic disease. However, the risk of allergen specific immunotherapy-related systemic reactions (SRs), reported to occur in approximately 1% to 14% of patients and which can range from mild to fatal in seriousness, represents a barrier to implementing this unique and effective treatment option.

Objective: To explore the possibility that pretreatment with the H1-antihistamine fexofenadine could prevent the occurrence of severe SRs induced by immunotherapy in Japanese patients with allergic rhinitis.

A case of calcific retropharyngeal tendinitis suspected to be a retropharyngeal abscess upon the first medical examination.

We report a case of calcific retropharyngeal tendonitis that was difficult to distinguish from retropharyngeal abscess. The patient was a 34-year-old woman who complained of severe cervical pain and stiffness for 1 day. She had a fever and moderately elevated WBC.

The role of estrogen and Cu, Zn-SOD on histological changes after menopause in female rat parotid.

Objective: Generally, postclimacteric women are susceptible to xerostomia. Therefore, correlations between xerostomia and sex hormones have been studied. Previously, we reported that a reduction of estrogen (belongs to female hormones) could have influence on age-related histological changes in female rat parotids induced by apoptosis.

Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.

Background: The processes of malignant tumour invasion and metastasis are known to include the destruction of cell stroma and vascular basement membrane. It has been suggested that type IV collagenase degrades type IV collagen, a main component of the basement membrane.

Methods: In our study, type IV collagenase activity in human thyroid tumours was measured by the Liotta method.

Histopathological findings of human thyroid tumors and dynamic MRI.

Objective: Time intensity curves for gadolinium-diethylenetriaminepentaceticacid (Gd-DTPA) enhanced magnetic resonance imaging (MRI), namely dynamic MRI, were determined for thyroid diseases, and compared with findings of histopathologic examination.

Methods: Time intensity curves for the thyroid tumors were determined. Three different patterns of time intensity curves were observed: a rapid washout pattern, a delayed washout pattern and no change.

Correlation between morphology of colonies formed by human thyroid tumor cells in collagen gel culture and invasive ability.

Two different types of colonies from human thyroid papillary carcinomas were observed in collagen gel culture. One was a branching type, with many three-dimensional outgrowths. The other was a spherical type, with no outgrowths.