Publications by authors named "Kiyoshi Yokoyama"
The overexpression of murine double minute 2 (MDM2) is found in several human tumors, and increased expression of MDM2 inactivates the apoptotic and cell cycle arrest function of p53. Interleukin-16 (IL-16) is a pleiotrophic cytokine and the properties of IL-16 suggest that it involve in the pathophysiological process of chronic inflammatory diseases. In this study, we investigated the expression of MDM2 in intestinal metaplasia and gastric cancer as well as the effect of H.
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- Schönlein-Henoch purpura (SHP) is a systemic condition marked by purpura and leukocytoclastic vasculitis, where diagnosing the condition can be challenging if gastrointestinal symptoms appear before the purpura.
- In a study of 11 SHP cases, abdominal pain was present in all, with diarrhea in 4 and bloody stools in 3; endoscopic findings revealed significant issues in the stomach, small intestine, and large intestine.
- The study highlights the need for awareness of specific endoscopic findings and thorough observation of gastrointestinal symptoms for accurate SHP diagnosis, especially when GI symptoms precede skin manifestations.
A 38-year-old woman was referred to our institution due to epigastralgia. She presented with obstructive jaundice and eosinophilia. Endoscopic retrograde cholangiopancreatography showed diffuse narrowing from the distal common bile duct to the bifurcation of the hepatic ducts.
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