Publications by authors named "Kiyoshi Otsuka"
Article Synopsis
- * In a study of 88 Japanese T2DM patients, HbA1c levels decreased by an average of 1.24% and body weight reduced by 1.44 kg after 6 months of oral semaglutide treatment.
- * The treatment led to a significant increase in the percentage of patients achieving HbA1c levels below 7%, improving various cardiometabolic parameters regardless of factors like age and kidney
Article Synopsis
- OW semaglutide, a once-weekly GLP-1 receptor agonist, was found to lower glycated hemoglobin (HbA1c) more effectively than other oral diabetes medications in Japanese patients with type 2 diabetes in a real-world setting.
- * The study tracked 77 patients over 6 months, showing an average HbA1c decrease of 0.89% and an increase in patients achieving HbA1c levels below 7% from 21% to 43%.
- *Factors such as higher baseline HbA1c and shorter duration of diabetes predicted better responses, and the treatment was mostly well tolerated among the participants.*
Infliximab shows drastic efficacy for controlling inflammation in rheumatoid arthritis (RA), though the ideal dose of infliximab to keep suppressing inflammation has not yet been identified. Recently, it has been evidenced that the minimum trough serum infliximab levels required for suppressing inflammation are greater than 1 µg/mL. This cross-sectional study was designed to identify the minimum dosage of infliximab for maintaining serum infliximab levels greater than 1 µg/mL.
View Article and Find Full Text PDFElectrochemical oxidative carbonylation of methanol was studied over Au supported carbon anode in CO. The major carbonylation products were dimethyl oxalate (DMO) and dimethyl carbonate (DMC). The minor oxidation products were dimethoxy methane (DMM) and methyl formate (MF) from methanol and CO(2).
View Article and Find Full Text PDFNew and unique electrocatalysis of gold for the carbonylation of methanol to dimethyl oxalate (DMO) and dimethyl carbonate (DMC) was found. The selectivity to DMO and DMC could be controlled over gold anode by electrochemical potential, as you like. Drastic changes of gold electrocatalysis was due to changes of the oxidation state of gold, Au0 or Au3+.
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