Can dual-time-point 18F-FDG PET/CT differentiate malignant salivary gland tumors from benign tumors?

Objective: The purpose of this study is to evaluate the usefulness of dual-time-point 18F-FDG PET/CT for discriminating between benign and malignant salivary gland tumors.

Materials And Methods: Dual-time-point FDG PET/CT images of 40 salivary gland tumors (20 benign and 20 malignant) were evaluated retrospectively. The maximum standardized uptake values (SUVmax) in the early and delayed phases and the retention index of each tumor were calculated and compared between benign and malignant tumors by the Mann-Whitney U test.

Optimal timing of post-treatment [18F]fluorodeoxyglucose-PET/CT for patients with head and neck malignancy.

Objectives: The aims of this study were to evaluate the ability of [F]fluorodeoxyglucose (F-FDG)-PET/computed tomography (CT) to identify tumor recurrence, nodal metastases, and distant metastases for surveillance and discuss the optimal timing of F-FDG-PET/CT examination after the completion of treatment for head and neck malignancy.

Methods: A total of 319 patients who underwent a post-treatment F-FDG-PET/CT examination for head and neck malignancy were studied. F-FDG-PET/CT findings were compared with the final diagnosis confirmed by histopathological examinations or clinical and radiological follow-up for at least 6 months.

Magnetic resonance imaging of temporomandibular joint cyst.

Objective: The objective of this study was to evaluate the magnetic resonance imaging (MRI) and clinical findings of 6 cases with synovial or ganglion cysts occurring in the temporomandibular joint (TMJ).

Study Design: Six patients with histopathologically confirmed TMJ cysts who were examined by MRI were included in this study. Two oral radiologists retrospectively evaluated MR images.

Longitudinal MRI follow-up of rheumatoid arthritis in the temporomandibular joint: importance of synovial proliferation as an early-stage sign.

This article describes longitudinal magnetic resonance imaging (MRI) observations in a patient with rheumatoid arthritis of the temporomandibular joint. The characteristic findings included marked synovial proliferation, which was observed before the onset of severe bone destruction. MRI is considered to provide valuable information for the early detection of rheumatoid arthritis of the temporomandibular joint.

Dual-time-point fluorodeoxyglucose positron emission tomography for diagnosis of cervical lymph node metastases in patients with head and neck squamous cell carcinoma.

Objective: The purpose of this study was to evaluate whether dual-time-point fluorodeoxyglucose positron emission tomography/computed tomography image can improve nodal diagnosis in patients with head and neck squamous cell carcinoma (HNSCC).

Methods: One hundred six HNSCC patients were enrolled. Positron emission tomography/computed tomography images were obtained twice: 1 and 2 hours after fluorodeoxyglucose injection.

[18F]Fluorodeoxyglucose-PET/CT differentiation between physiological and pathological accumulations in head and neck.

Objectives: The purposes of this study were to evaluate various physiological fluorodeoxyglucose (FDG) accumulations in the head and neck and to compare those with tumor (pathological) FDG accumulation.

Methods: One hundred and twelve patients with head and neck carcinomas were studied. PET/computed tomography examinations were performed 1 h after intravenous injection of fluorine-18-labeled FDG.

Diagnostic accuracy of cone-beam CT in the assessment of mandibular invasion of lower gingival carcinoma: comparison with conventional panoramic radiography.

Purpose: To evaluate the diagnostic accuracy of cone-beam CT in assessing mandibular invasion by lower gingival carcinoma and compare it with that of panoramic radiography.

Patients And Methods: Fifty patients with squamous cell carcinoma of the lower gingiva who were examined by both panoramic radiography and cone-beam CT before surgery were included in this study. Five radiologists used a 6-point rating scale to independently evaluate cone-beam CT and panoramic images for the presence or absence of alveolar bone and mandibular canal involvement by tumor.

MRI findings of temporomandibular joints with disk perforation.

Objective: To investigate magnetic resonance imaging (MRI) findings of temporomandibular joints (TMJs) with disk perforation.

Study Design: Thirty-one TMJs (31 patients) with disk perforation, 37 TMJs (34 patients) with anterior disk displacement and no disk perforation, and 22 asymptomatic TMJs of 11 volunteers were examined by MRI. The presence or absence of disk perforation was confirmed by TMJ arthrography.

MRI and clinical findings of posterior disk displacement in the temporomandibular joint.

Objective: The objective of this study was to evaluate the magnetic resonance imaging and clinical findings of patients with posterior disk displacement in the temporomandibular joint.

Study Design: Magnetic resonance and clinical findings of 62 temporomandibular joints (44 patients) with posterior disk displacement were retrospectively analyzed.

Results: According to the criteria proposed by Westesson et al.

Tissue characterization of head and neck lesions using diffusion-weighted MR imaging with SPLICE.

Purpose: The purpose of this study was to evaluate the usefulness of diffusion-weighted (DW) MR imaging with split acquisition of fast spin-echo signals (SPLICE) in the tissue characterization of head and neck mass lesions.

Patients And Methods: DW MR images of 67 head and neck mass lesions were obtained using SPLICE with b-factors of 0 and 771s/mm(2). The lesions were classified into three categories: 16 cysts, 32 benign tumors, and 19 malignant tumors.

[Role of insulin-like growth factor-I receptor (IGF-IR) in survival kinetics and radioresistance of mouse embryo fibroblasts in a hypoxic environment].

The role of insulin-like growth factor-I receptor (IGF-IR) in survival kinetics and radioresistance of fibroblasts in a severely hypoxic environment (partial oxygen pressure of less than 3 mmHg) was analyzed, in both low and high cell-density conditions. Mouse embryonic fibroblasts R(-), with a targeted disruption of the IGF-IR gene, and R(+) cells, derived from R(-) cells stably transfected with a plasmid containing a human IGF-IR cDNA, were used for this purpose. Survival time in hypoxia was longer in R(+) cells than R(-) cells, which correlated with highly elevated expression of caspase 3-like activity in R(-) cells, but not with HIF-I alpha expression.