Publications by authors named "Kiyoshi Okihara"
Molasses of tangerine orange (Citrus unshiu Markovich) is obtained as a waste product in the course of tangerine orange juice production. This molasses is expected to be a useful source of organic compounds such as flavonoids and limonoids. To elucidate a use for this molasses waste, we isolated and identified its organic constituents.
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- The study investigated the effects of Brazilian propolis on scratching behavior in ICR mice, finding that propolis granular A.P.C significantly reduced scratching caused by compound 48/80 at high doses, but did not affect histamine-induced scratching.
- Propolis ethanol extract effectively inhibited histamine release from rat mast cells and blocked increased vascular permeability linked to compound 48/80.
- Repeated administration of propolis led to enhanced inhibition of scratching behavior, suggesting its effectiveness relies on a mast cell-dependent mechanism.
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- * The analysis revealed a specific sugar structure on the glycoprotein, linking various sugar components together.
- * This study is significant because it marks the first time an insect glycoprotein with a beta1-3 galactosylated N-glycan has been identified.
On a way of structural analysis of total N-glycans linked to glycoproteins in royal jelly (Kimura, Y. et al., Biosci.
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- The study investigated the impact of propolis granular A. P. C on lung tumors in female A/J mice, which were exposed to a tobacco-related carcinogen called NNK.
- Mice received NNK in their drinking water for 7 weeks while being fed a specific diet, and propolis A. P. C was given orally for 6 days a week beginning a week before NNK exposure.
- Results showed that mice treated with NNK alone had significantly more lung tumors compared to controls, but those given propolis A. P. C exhibited a notable decrease in tumor count, suggesting its potential as a suppressor of lung tumor development.
Occurrence of GalNAcbeta1-4GlcNAc unit in N-glycan of royal jelly glycoprotein.
Biosci Biotechnol Biochem
September 2002
Elsewhere, we characterized the structure of twelve N-glycans purified from royal jelly glycoproteins (Kimura, Y. et al., Biosci.
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