Publications by authors named "Kiyomichi Yoshimaru"

Background: For patients with acute myocardial infarction (AMI), several studies have examined the relationship between the metabolic syndrome and prognostic outcome. However, few studies have revealed an association between the metabolic syndrome and clinical outcomes in patients with unstable angina (UA). This study compared the differences in the usefulness of recognizing metabolic disorders for the prediction of a 1-year prognosis in patients with UA and AMI.

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Background: QT dispersion is increased in acute myocardial infarction (AMI), but the relation of QT dispersion to prognosis has not yet been fully elucidated.

Hypothesis: The purpose of this study is to evaluate prospectively whether QT dispersion is associated with the risk of major adverse cardiac events (MACEs) and mortality after successful coronary stenting in AMI.

Methods: One hundred and forty-two patients with AMI and undergoing successful percutaneous coronary intervention (PCI) were enrolled in this study.

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Objective: The reflection waveform in the ascending aortic pressure has been reported to reflect systemic arterial stiffness, and increase the risk of coronary heart disease. The purpose of this study is to evaluate prospectively whether the reflection waveform in the ascending aortic pressure is associated with the risk of major adverse cardiac events (MACE) after successful coronary stenting in acute myocardial infarction (AMI).

Methods And Results: One hundred and twenty-five patients with AMI and undergoing successful coronary stenting were enrolled in this study.

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Article Synopsis
  • QT dispersion increases in acute myocardial infarction (AMI) and its relationship with left ventricular (LV) function needs further research.
  • A study involving 75 AMI patients who had coronary stenting measured QT dispersion at various points before and after the procedure, with LV ejection fraction (LVEF) evaluated six months later.
  • The findings indicated that QT dispersion measured 24 and 48 hours after stenting has a significant correlation with LVEF six months later, suggesting these early measurements can help assess long-term heart function.
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Background: The reflection waveform in the ascending aortic pressure has been reported to reflect systemic arterial stiffness, and increase risk of coronary heart disease. The purpose of this study is to evaluate prospectively whether the reflection waveform in the ascending aortic pressure is associated with the mortality in patients with chronic renal failure on hemodialysis.

Methods: Fifty two patients with chronic renal failure on hemodialysis and undergoing cardiac catheterizations were enrolled in this study.

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It has been reported that the reflection waveform in the ascending aortic pressure is associated with systemic arterial stiffness. Stiffening of the aortic walls leads to a decrease in coronary perfusion and an increase in restenosis rate. The purpose of this study was to evaluate whether the reflection waveform in the ascending aortic pressure could be used to predict restenosis after percutaneous coronary stenting.

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Article Synopsis
  • Nicorandil, a potassium channel opener used to treat angina, was evaluated for its effects on QT dispersion and bradyarrhythmia during coronary angioplasty.
  • A study with 50 patients showed that those receiving nicorandil had significantly lower QT dispersion compared to the control group, suggesting reduced risk of heart rhythm issues.
  • The findings indicate that intravenous nicorandil is effective in minimizing QT dispersion and preventing bradyarrhythmia during the procedure.
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Background: Because nicorandil, a potassium channel opener, has a cardioprotective effect and attenuates reperfusion injury in patients with acute myocardial infarction (AMI), intravenous nicorandil should reduce arrhythmic mortality and QT dispersion in patients with AMI.

Objectives: The purpose of this study was to evaluate whether intravenous nicorandil reduces the occurrence of ventricular fibrillation and QT dispersion in patients with successful coronary angioplasty in AMI.

Methods: A historical cohort study on the effect of nicorandil on ventricular fibrillation and QT dispersion was conducted.

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We describe a patient with unstable angina due to occlusion of the orifice of the right coronary artery by thrombus formation after aortic valvular replacement using a Björk-Shiley valve. After strict anticoagulant treatment, transesophageal echocardiography demonstrated disappearance of the thrombus formation around the orifice of the right coronary artery.

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The authors describe the rare case of a patient with fusiform coronary aneurysm with myocardial infarction in the left circumflex artery complicated by idiopathic thrombopenia. Medical treatment with a combination of warfarin and aspirin could not prevent recurrence of angina pectoris and myocardial infarction, but surgical ligation of the proximal site of the fusiform aneurysm and coronary bypass to the distal site of the fusiform aneurysm prevented further myocardial infarction and angina pectoris.

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Background: Although it was reported that the pulsatility of ascending aortic pressure is closely related to restenosis after percutaneous transluminal coronary angioplasty (PTCA), it is not known whether the reflection period of ascending aortic pressure can predict restenosis after PTCA. The purpose of this study was to evaluate whether reflection in the arterial system can be used to predict restenosis after PTCA.

Methods: We used the inflection point as the reflection period index and measured the coronary artery diameter, aortic pressure, and inflection time before PTCA.

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Background: Although it was reported that the augmentation index and inflection time are closely related to reflection in the arterial system and large artery function, it is not known whether these indices of the ascending aortic pressure waveform increase the risk of coronary heart disease (CHD). The purpose of this study was to evaluate whether the aortic reflection of the ascending aortic pressure waveform is related to an increased risk of CHD.

Methods: We enrolled 190 men and women who had chest pain, normal contractions, no local asynergy, and no history of myocardial infarction.

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