Intracellular interplay between cholecystokinin and leptin signalling for satiety control in rats.

Cholecystokinin (CCK) and leptin are satiety-controlling peptides, yet their interactive roles remain unclear. Here, we addressed this issue using in vitro and in vivo models. In rat C6 glioma cells, leptin pre-treatment enhanced Ca mobilization by a CCK agonist (CCK-8s).