[Combined treatment of patients with oral tumors with extracorporeal neutron-photon therapy].

Combined therapy with preoperative course of remote neutron therapy was given to 29 patients with oral cavity cancer. All the patients had stage III of morphologically verified squamous cell carcinoma. Partial tumor regression after radiotherapy was observed in 39.

[Reversible erythrocyte aggregation in cancer patients].

Reversible aggregation of the peripheral blood erythrocytes was studied in patients with stages III-IV lung cancer and patients with stages II-III tumors of the head and neck (cancer of the tongue, larynx, and buccal mucosa). The parameters examined were as follows: U0 and Ud--minimal and maximal stability of aggregates, tau---red cell aggregation half-period, A--the amplitude of photometric signal (in mm) characterizing the count of erythrocytes, Ia--aggregation index, and K--integral coefficient. The findings indicate an appreciable intensification of reversible aggregation of red cells in cancer: a significant increase of U0, Ud, A, Ia, and K and decrease of tau.

[Surface architectonic of the peripheral red blood cells in cancer patients].

Scanning electron microscopy of the relief of the surface of peripheral red blood cells in patients with tumors of the head and neck (cancer of the tongue, larynx, and fundal buccal mucosa) of stages II-III and with stages III-IV lung cancer revealed similar changes, characterized by a manifest drop in the count of discocytes and increased share of transitional, prehemolytic, and degenerative forms of cells.

[The use of low-energy lasers for preventing and treating postoperative and radiation-induced complications in patients with head and neck tumors].

The efficacy of low-energy helium-neon and copper vapor lasers for prevention and treatment of postoperative and irradiation complications was assessed in 195 patients with locally advanced tumors of the head and neck. The control group included 118 patients. Intravenous laser irradiation of the blood was associated with a higher percentage of wound healing by first intention and better course of the postoperative period.

[Intravascular laser irradiation of the blood in treating suppurative-necrotic processes of the maxillofacial area].

The results of investigations evidence a high efficacy of intravascular laser irradiation of the blood in the treatment of maxillofacial pyonecrotic processes. Such treatment is conducive to improvement of the immunologic reactivity, microcirculation, and regeneration. The method is simple, that recommends it for outpatient practice.

[Long-term radiation injuries following neutron therapy].

The paper is concerned with the data on late radiation injuries of normal tissues and critical organs in a group of 35 patients after fast neutron therapy in a period of 12 mos.-3.5 yrs.

[Primary reconstructive operations in cancer of the mouth mucosa and oropharynx].

An analysis of primary reconstructive surgical treatment of 254 patients with carcinoma of the mouth mucosa and oral pharynx was made. The character of operative procedures for different localizations of the tumour is described. The primary reconstructive surgical treatment was shown to reduce the amount of postoperative complications to 11.

[Plastic surgery of postoperative defects in patients with tumors of the maxillofacial area].

Defects resulting from surgical treatment for maxillo-facial tumors of various origin were studied. Procedures for reconstruction versus site are discussed and immediate results are presented. Reconstruction should be performed in early postoperative period to assure normal food passage.

[3 years' experience of radiation therapy with fast neutrons on the V-120 cyclotron].

The paper discusses the results of treatment of 128 patients with head and neck cancer in whom fast neutrons (Y-120; approximately 6.2 MeV) were used as a single procedure or in combination with surgery. Tumors of different histomorphologic structure displayed unequal sensitivity to fast neutrons.

[The postoperative period in malignant tumors of the paranasal sinuses following preoperative and radical regimens of neutron therapy].

Surgical intervention was performed in 16 patients with advanced tumors of the accessory sinuses and nose receiving neutron teletherapy. The 1st group (10 persons) was treated by combined therapy including preoperative irradiation with fast neutrons: 2 fractions a week at a dose of 1.2-1.

[Neutron therapy of head and neck tumors].

The results of therapy of 55 head and neck tumor patients using fast neutrons of the Y-120 cyclotron of the Research Institute of Nuclear Physics, Tomsk Polytechnical Institute, were analyzed. For design of courses of neutron and combined neutron-photon therapy formulas of DMF calculation were used in cases of homogeneous and arrhythmic dose fractionation. The authors presented some data on methods of therapy with fast neutrons, dose fractionation schedules, a focal dose value, and time of treatment.

[Experience in using the small PMB-6E betatron for the radiation treatment of oncological patients].

The paper is concerned with the first results of treatment of 46 patients with tumors of the skin, oral mucosa and other sites using the Soviet small-size PMB-6E betatron with the energy of fast electrons at 6 MeV. The performance of the unit and different variants of dosimetric therapeutic plans of the fast electron beam are presented. Electron therapy with the energy of 6 MeV was mostly used in patients with head and neck tumors.