[Effect of emotional painful stress on affinity of blood to oxygen, on the antioxidant system and physical properties of the hepatocyte microsomal membrane].

The emotional-painful stress causes a more pronounced decrease in affinity of hemoglobin to oxygen in portal blood compared with mixed blood. This contributes to increased oxygen pressure in hepatocytes and activates free radical processes in liver microsomes. Activation of lipid peroxidation is accompanied by changes in physical properties (microviscosity, polarity) of microsomal membranes.