Objective: To investigate leptin gene variations in Thai primary school children.
Material And Method: Direct DNA sequencing was performed following polymerase chain reaction (PCR) amplification of the leptin gene in 30 obese children aged 10-12 years old.
Results: A heterozygous variant 19 (G > A), located in the non-coding region of exon 1 was detected in 13 subjects (43.