Publications by authors named "Kishore Vedala"

Introduction: The distribution of cerebral age-related white matter changes (ARWMC) may be indicative of the underlying etiology and could suggest optimal interventions. We aimed to determine if left ventricular hypertrophy (LVH), a marker of uncontrolled hypertension, along with additional risk factors are associated with the distribution of cerebral ARWMC.

Methods: We analyzed data of 172 patients from a hospital stroke registry who had acute stroke and brain MRI.

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Objective: Transcranial Magnetic Stimulation (TMS) has emerged as a viable non-invasive method for mapping language networks. Little is known about the tolerability of transcranial magnetic stimulation language mapping in children.

Methods: Children aged 5-18 years underwent bilateral language mapping using repetitive transcranial magnetic stimulation (rTMS) to target 33 sites/hemisphere.

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Article Synopsis
  • The study compares the effectiveness and safety of electrical stimulation mapping (ESM) using subdural electrodes (SDE) and stereoelectroencephalography (SEEG) in functional brain localization for patients with epilepsy.
  • Results showed similar language and motor responses between the two methods, but SEEG had a higher incidence of sensory responses and less frequent afterdischarges (ADs) and EISs (unwanted seizures).
  • Overall, SEEG is considered a safer and more effective option for functional brain mapping due to its favorable thresholds and capacity for identifying sensory areas compared to SDE.
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Objective: Age-related cerebral white matter abnormalities, commonly termed leukoaraiosis (LA), are frequent manifestation of cerebral microvascular disease. Aging and hypertension are well linked to LA. We compared additional vascular risk factors and socioeconomic factors with LA severity in acute stroke patients.

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Background And Purpose: Up to 30% of acute stroke evaluations are deemed stroke mimics, and these are common in telestroke as well. We recently published a risk prediction score for use during telestroke encounters to differentiate stroke mimics from ischemic cerebrovascular disease derived and validated in the Partners TeleStroke Network. Using data from 3 distinct US and European telestroke networks, we sought to externally validate the TeleStroke Mimic (TM) score in a broader population.

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