Primary Extradural Meningioma: A Systematic Review of Diagnostic Features, Clinical Management, and Surgical Outcomes.

This systematic review consolidates the literature on primary extradural meningiomas (PEMs), a rare subset of meningiomas. We describe the clinical features, management strategies used, and treatment outcomes for published cases. A systematic review was conducted using PRISMA guidelines across multiple databases to 29 July 2024.

Mixed Gangliocytoma-Pituitary Adenoma: A Systematic Review of Diagnostic Features, Clinical Management, and Surgical Outcomes.

Objective: Mixed gangliocytoma-pituitary adenomas (MGPAs) are very rare sellar neoplasms. Contemporary understanding of their natural history, clinical characteristics, optimal management strategies, and prototypical outcomes remains poorly understood.

Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PubMed, Embase, Web of Science, and Cochrane were searched to include studies of patients with histologically confirmed mixed gangliocytomas.

A dual-luciferase bioluminescence system for the assessment of cellular therapies.

Bioluminescence imaging is a well-established platform for evaluating engineered cell therapies in preclinical studies. However, despite the discovery of new luciferases and substrates, optimal combinations to simultaneously monitor two cell populations remain limited. This makes the functional assessment of cellular therapies cumbersome and expensive, especially in preclinical models.

Surgical intervention ≤ 24 hours versus > 24 hours after injury for the management of acute traumatic central cord syndrome: a systematic review and meta-analysis.

Objective: The objective was to evaluate the efficacy, outcomes, and complications of surgical intervention performed within 24 hours (≤ 24 hours) versus after 24 hours (> 24 hours) in managing acute traumatic central cord syndrome (ATCCS).

Methods: Articles pertinent to the study were retrieved from PubMed, Scopus, Web of Science, and Cochrane. The authors performed a systematic review and meta-analysis of treatment procedures and outcomes according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRIMSA) guidelines.

Delta Radiomic Features Predict Resection Margin Status and Overall Survival in Neoadjuvant-Treated Pancreatic Cancer Patients.

Background: Neoadjuvant therapy (NAT) emerged as the standard of care for patients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgery; however, surgery is morbid, and tools to predict resection margin status (RMS) and prognosis in the preoperative setting are needed. Radiomic models, specifically delta radiomic features (DRFs), may provide insight into treatment dynamics to improve preoperative predictions.

Methods: We retrospectively collected clinical, pathological, and surgical data (patients with resectable, borderline, locally advanced, and metastatic disease), and pre/post-NAT contrast-enhanced computed tomography (CT) scans from PDAC patients at the University of Texas Southwestern Medical Center (UTSW; discovery) and Humanitas Hospital (validation cohort).

Urethral pyogenic granuloma in an adult patient: Presentation and management.

Pyogenic granulomas (PGs) are benign vascular tumors that are commonly found on cutaneous and mucosal surfaces. However, mucosal PGs are rarely found in the urogenital tract. Here, we report a case of PG arising from the urethra in a 68 year-old female.

Correction to: Optimized adaptive neuro-fuzzy inference system based on hybrid grey wolf-bat algorithm for schizophrenia recognition from EEG signals.

[This corrects the article DOI: 10.1007/s11571-022-09817-y.].

Cesium-131 brachytherapy for the treatment of brain metastases: Current status and future perspectives.

Adjuvant radiotherapy is often necessary following surgical resection of brain metastases to improve local tumor control and survival. Brachytherapy using cesium-131 offers a novel method for loco-regional radiotherapy. We reviewed the current literature reporting the use of cesium-131 brachytherapy for the treatment of brain metastases.

Optimized adaptive neuro-fuzzy inference system based on hybrid grey wolf-bat algorithm for schizophrenia recognition from EEG signals.

Schizophrenia is a chronic mental disorder that impairs a person's thinking capacity, feelings and emotions, behavioural traits, etc., Emotional distortions, delusions, hallucinations, and incoherent speech are all some of the symptoms of schizophrenia, and cause disruption of routine activities. Computer-assisted diagnosis of schizophrenia is significantly needed to give its patients a higher quality of life.

Tumors Involving the Infratemporal Fossa: A Systematic Review of Clinical Characteristics and Treatment Outcomes.

Background: Infratemporal fossa (ITF) tumors represent various pathologies and are seldom described in the literature, reflecting their rarity. Here we review the literature on tumors invading ITF and describe patient characteristics, treatment strategies, and clinical outcomes.

Methods: Relevant articles were retrieved from PubMed, Scopus, and Cochrane.

Secreted Fas Decoys Enhance the Antitumor Activity of Engineered and Bystander T Cells in Fas Ligand-Expressing Solid Tumors.

T-cell immunotherapy has demonstrated remarkable clinical outcomes in certain hematologic malignancies. However, efficacy in solid tumors has been suboptimal, partially due to the hostile tumor microenvironment composed of immune-inhibitory molecules. One such suppressive agent abundantly expressed in solid tumors is Fas ligand (FasL), which can trigger apoptosis of Fas-expressing effector cells such as T cells and natural killer (NK) cells.

Adenoid Cystic Carcinoma (ACC) Infiltrating the Skull Base: A Systematic Review of Clinical Characteristics and Management Strategies.

Background/aim: To systematically review the patient characteristics and management approaches of adenoid cystic carcinoma (ACC) infiltrating the skull base.

Materials And Methods: According to PRISMA guidelines, PubMed, Scopus, and Cochrane were searched to retrieve studies reporting management protocols and survival outcomes of patients with skull base ACCs. Patient characteristics, management strategies, and outcomes were investigated.

Supplementary Motor Area Syndrome After Brain Tumor Surgery: A Systematic Review.

Background: Supplementary motor area syndrome (SMAS) may occur after frontal tumor surgery, with variable presentation and outcomes. We reviewed the literature on postoperative SMAS after brain tumor resection.

Methods: PubMed, Web of Science, Scopus, and Cochrane were searched following the PRISMA guidelines to include studies reporting SMAS after brain tumor resection.

The role of cesium-131 brachytherapy in brain tumors: a scoping review of the literature and ongoing clinical trials.

Purpose: Cesium-131 radioactive isotope has favored the resurgence of intracavitary brachytherapy in neuro-oncology, minimizing radiation-induced complications and maximizing logistical and clinical outcomes. We reviewed the literature on cesium-131 brachytherapy for brain tumors.

Methods: PubMed, Web-of-Science, Scopus, Clinicaltrial.

Evaluating the Optimal Management of Inoperable Giant Cell Tumors of the Spine: A Systematic Review and Meta-Analysis.

Background: Surgical resection remains the preferred treatment in spine giant cell tumors (SGCTs), but it is not always feasible. Conservative strategies have been studied for inoperable cases. We systematically reviewed the literature on inoperable SGCTs treated with denosumab, radiotherapy or selective arterial embolization (SAE).

Posterior epidural intervertebral disc migration and sequestration: A systematic review.

Posterior epidural intervertebral disc migration and sequestration (PEIMS) is a rare and debilitating complication of degenerative disc disease. Radiological differential diagnosis is often challenging, complicating the accurate planning of appropriate treatment strategies. We systematically reviewed the literature on PEIMS, focusing on clinical-radiological features and available treatments.

Spontaneous intracerebral pseudoaneurysm rupture and meningiomatosis: A case report and review of the literature.

Background: We report the first case of a spontaneous ruptured anterior cerebral artery pseudoaneurysm in a patient affected by meningiomatosis.

Case Description: A 71-year-old female patient was admitted to our emergency department after acute loss of consciousness. An urgent head CT scan showed third ventricle hemorrhage and a giant extra-axial tumor with associated peritumoral bleeding.

Prediction of neuro-degenerative disorders using sunflower optimisation algorithm and Kernel extreme learning machine: A case-study with Parkinson's and Alzheimer's disease.

Parkinson's and Alzheimer's Disease are believed to be most prevalent and common in older people. Several data-mining approaches are employed on the neuro-degenerative data in predicting the disease. A novel method has been built and developed to diagnose Alzheimer's (AD) and Parkinson's (PD) in early stages, which includes image acquisition, pre-processing, feature extraction and selection, followed by classification.

Cardiovascular Risk Factors, Cognitive Dysfunction, and Mild Cognitive Impairment.

Objectives: The present study sought to evaluate the contribution of cardiovascular risk factors to cognitive functioning in a sample of Mexican Americans diagnosed with mild cognitive impairment (MCI).

Methods: Hypertension, diabetes, dyslipidemia, and obesity were diagnosed based on self-report and/or standardized procedures. Cognitive function was measured with MMSE, Logical Memory I and II, Trail A & B, FAS, animal naming, and digit span tests.

Improved adaptive neuro-fuzzy inference system based on modified glowworm swarm and differential evolution optimization algorithm for medical diagnosis.

Medical diagnosis has seen a tremendous advancement in the recent years due to the advent of modern and hybrid techniques that aid in screening and management of the disease. This paper figures a predictive model for detecting neurodegenerative diseases like glaucoma, Parkinson's disease and carcinogenic diseases like breast cancer. The proposed approach focuses on enhancing the efficiency of adaptive neuro-fuzzy inference system (ANFIS) using a modified glowworm swarm optimization algorithm (M-GSO).

State-of-the-Art Techniques in Optic Cup and Disc Localization for Glaucoma Diagnosis: Research Results and Issues.

Glaucoma is a heterogeneous group of diseases that are characterized by loss of retinal ganglion cells, which damages the optic nerve head (ONH) and visual field. If glaucoma, the most frequent cause of irretrievable vision loss, is detected at an initial stage, the rate of blindness may be reduced by nearly 50%-55%. Manual diagnosis is a laborious task; it is fairly time consuming and requires a skilled medical provider.