Publications by authors named "Kisho Iizuka"

Article Synopsis
  • Neoculin is a sweet protein from the fruit of Curculigo latifolia that can convert sour flavors into sweet ones.
  • It has the unique ability to make drinking water taste sweet, suggesting that it can affect non-acidic compounds.
  • Research shows that ammonium chloride and specific amino acids trigger neoculin's sweetness, making it useful for enhancing the flavor of foods rich in amino acids.
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Neoculin has pH-dependent taste-modifying activity. This study found that neoculin changed pH-dependently in its tryptophan- and ANS-derived fluorescence spectra, while no such change occurred in a neoculin variant whose histidine residues were replaced with alanine. These results suggest that the sweetness of neoculin depends on structural change accompanying the pH change, with the histidine residues playing a key role.

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