Publications by authors named "Kishen Lachireddy"
In April 2021, the South Eastern Sydney Local Health District Public Health Unit (Sydney, New South Wales, Australia) was notified of 3 patients with Pseudomonas aeruginosa infections secondary to skin piercings performed at the same salon. Active case finding through laboratories, clinician alerts, and monitoring hospital visits for piercing-related infections identified additional cases across New South Wales, and consumers were alerted. We identified 13 confirmed and 40 probable case-patients and linked clinical isolates by genomic sequencing.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the environmental factors contributing to the rise in Ross River virus (RRV) and Barmah Forest virus (BFV) cases, particularly after heavy rainfall and high tides, to improve public health responses in the future.
- It was found that after two dry years, a significant rainfall event in February 2020 led to a spike in mosquito populations, which preceded increases in RRV and BFV notifications by several weeks.
- The research underscores the importance of timely mosquito bite prevention measures following heavy rain, especially in light of climate change and the emergence of new viruses like Japanese encephalitis in Australia.
Article Synopsis
- Button battery ingestion is a growing global concern, particularly noted in Australia, where healthcare system shortcomings have led to treatment delays and increased risks, especially among children.
- A study conducted by the Australian Poisons Information Centre analyzed 578 button battery exposure cases, revealing that many incidents involved young children and batteries from common household items like toys and remote controls.
- The findings suggest that educational campaigns, improved professional guidelines, and enhanced safety features could help mitigate the dangers of button battery ingestion and improve response times in healthcare settings.
Climate change, health and wellbeing: challenges and opportunities in NSW, Australia.
Public Health Res Pract
December 2018
The NSW (New South Wales) Climate Change Policy Framework, launched by the NSW Government in 2016, recognises that climate change presents risks to health and wellbeing. Risks to health and wellbeing come from direct impacts of extreme weather events, and from indirect impacts through effects on air, water, food and ecosystems. Responding to these challenges offers an opportunity to protect and promote health by enhancing environmental amenities, and building adaptive capacity and resilience in populations and systems.
View Article and Find Full Text PDFA systematic review of the health risks from passive exposure to electronic cigarette vapour.
Public Health Res Pract
April 2016
Objectives: Electronic cigarettes (ECs) have recently become popular around the world, and their safety is being widely discussed in the scientific literature. Previous studies have examined the chemicals in e-liquids and vapour, and demonstrated that the aerosol from ECs can contain toxic chemicals that are harmful to health. However, little is known about the potential adverse health effects of passive exposure to EC vapour.
View Article and Find Full Text PDFBackground: Highly active antiretroviral therapy (HAART) can successfully reduce plasma and tissue levels of HIV-1 RNA and results in reductions in HIV-related morbidity and mortality, but the slow viral evolution during therapy in cellular reservoirs is a continuing problem. In addition, little remains known how viral evolutionary process may differ between cell-free and cell-associated compartments, over time, in vivo in patients receiving HAART or STI.
Objectives: The main objectives of this study were to assess viral replication kinetics, drug resistance and viral evolution during HAART and STI.
Background: Very little is known about the influence of Highly Active Antiretroviral Therapy (HAART) on the surface expression of CCR5 and CXCR4 with respect to receptor tropism and replication kinetics of autologous HIV strains, during continuous therapy and structured treatment interruption (STI) regimens.
Objectives: The main objectives of this study were to assess whether continuous therapy and STI regimens had any modulatory effects on expression of CCR5 and CXCR4 on T lymphocytes.
Study Design: We studied 6 patients on continuous HAART, 4 patients on STI and 1 treatment-naïve patient.