Graft verus host disease (GVHD) following Liver transplantation is rare life threatening complication with very high mortality rate around 85%. Due to increased recognition of this condition management approach is rapidly evolving due to newer diagnostic methods and drugs. Etiology, risk factors, pathogenesis, preventive strategies, management approach and newer drugs are discussed.
View Article and Find Full Text PDFBackground: Nations with emerging deceased-donor liver transplantation programs, such as India, face problems associated with poor donor maintenance. Cold ischemic time (CIT) is typically maintained short by matching donor organ recovery and recipient hepatectomy to achieve maximum favorable outcome. We analyzed different extended criteria donor factors including donor acidosis, which may act as a surrogate marker of poor donor maintenance, to quantify the risk of primary nonfunction (PNF) or initial poor function (IPF).
View Article and Find Full Text PDFBackground: Distal duodenal and duodenojejunal flexure tumors are rare. They present late due to vague symptomatology and difficulties in establishing a diagnosis. Due to vague symptoms, these tumors would have had spread locally or metastasized to regional nodes or distant organs at presentation.
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