soft tissue regenerative potential of flax seed mucilage self-assembled collagen aerogels.

The present study demonstrates thesoft tissue regenerative potential of flax seed mucilage (FSM) reinforced collagen aerogels in Wistar rats. The physiochemical, mechanical, and thermal properties were significantly improved upon the incorporation of flax mucilage into collagen when compared to the native collagen scaffold. In addition, the functional group of flax mucilage notably contributed to a better anti-oxidative potential than the control collagen.

SARS-CoV-2 spike protein: Site-specific breakpoints for the development of COVID-19 vaccines.

SARS-CoV2 is a member of human coronaviruses and is the causative agent of the present pandemic COVID-19 virus. In order to control COVID-19, studies on viral structure and mechanism of infectivity and pathogenicity are sorely needed. The spike (S) protein is comprised of S1 & S2 subunits.

Effect of naturally isolated hydroquinone in disturbing the cell membrane integrity of MTCC 741 and MTCC 740.

Nosocomial pathogens cause various health problems in human and many novel drugs are under investigation to combat the pathogens. The present study explains the naturally derived hydroquinone possible mode of action against MTCC 741 and MTCC 740. Time kill studies, cell viability assays, membrane potential assays, and potassium release assays were carried out to study the mode of action.

Surface engineered iron oxide nanoparticles as efficient materials for antibiofilm application.

Overuse of antibiotics has led to the development of multidrug-resistant strains. Antibiotic resistance is a major drawback in the biomedical field since medical implants are prone to infection by biofilms of antibiotic resistant strains of bacteria. With increasing prevalence of antibiotic-resistant pathogenic bacteria, the search for alternative method is utmost importance.