Prediction of coronary heart disease or heart failure using high-sensitivity cardiac troponin T: A pilot study.

Background: High-sensitivity cardiac troponin T (hs-cTnT) is a good prognostic marker for mortality. However, it is uncertain if hs-cTnT can be used to detect sub-clinical cardiac disease.

Method: Pilot study in patients without known heart disease and elevated hs-cTnT measured at presentation to the emergency department.

High-sensitivity cardiac troponin T is superior to troponin I in the prediction of mortality in patients without acute coronary syndrome.

Background: Differences in prevalence and prognostic information of cardiac troponin T (cTnT) and I (cTnI) concentrations in patients without acute coronary syndrome (ACS) are insufficiently investigated. High-sensitivity assays (hs-cTn) have led to an increased interest in hs-cTn for risk stratification. Here, we compare hs-cTnT and hs-cTnI in prediction of mortality patients without ACS.

Prevalence and significance of troponin elevations in patients without acute coronary disease.

Background: Cardiac troponin T and I are important diagnostic and prognostic markers in patients with acute coronary syndrome (ACS). Troponin elevations in various non-ACS scenarios have been documented, but few studies have been conducted on the general hospitalized population, none compared the diagnostic performance of troponin I and T.

Methods And Results: Patients aged >18years (n=1097), consecutively admitted to a district hospital, were included in the study.