Publications by authors named "Kirsten de Groote"
Horm Res Paediatr
June 2024
Article Synopsis
- The study investigates the clinical impacts of heterozygous IGF1 variants, which are linked to growth failure, microcephaly, and other developmental issues, but lacks extensive treatment knowledge.
- Nine patients were analyzed, revealing various genetic deletions and growth measurements, with many experiencing feeding difficulties and significantly low growth metrics.
- After 1-2 years of recombinant human growth hormone treatment, patients showed growth improvements, with some achieving adult heights taller than initially forecasted.
