[Cognitive deficits in epilepsy].

Cognitive deficits are common in people with epilepsy and may have impact on education, work, and personal life. Furthermore, cognitive symptoms are often present before seizure onset and often persist upon seizure freedom. As presented in this review, epilepsy is more than just seizures and alike epileptic activity, cognitive dysfunction is a symptom of underlying pathophysiology of the brain and a condition which needs to be addressed when the diagnosis of epilepsy is set.

[Epilepsy surgery].

Surgery is the only treatment option with the potential to cure epilepsy. This review is a description of the multidisciplinary and multimodal presurgical evaluation process and the outcome of the Danish epilepsy surgery programme. The outcome aligns with international results and serious complications to surgery are very rare.

Verbal learning and memory outcome in selective amygdalohippocampectomy versus temporal lobe resection in patients with hippocampal sclerosis.

Purpose: With the advent of new very selective techniques like thermal laser ablation to treat drug-resistant focal epilepsy, the controversy of resection size in relation to seizure outcome versus cognitive deficits has gained new relevance. The purpose of this study was to test the influence of the selective amygdalohippocampectomy (SAH) versus nonselective temporal lobe resection (TLR) on seizure outcome and cognition in patients with mesial temporal lobe epilepsy (MTLE) and histopathological verified hippocampal sclerosis (HS).

Methods: We identified 108 adults (>16years) with HS, operated between 1995 and 2009 in Denmark.

Aphasia after stroke: type, severity and prognosis. The Copenhagen aphasia study.

Aim: To determine the types, severity and evolution of aphasia in unselected, acute stroke patients and evaluate potential predictors for language outcome 1 year after stroke.

Methods: 270 acute stroke patients with aphasia (203 with first-ever strokes) were included consecutively and prospectively from three hospitals in Copenhagen, Denmark, and assessed with the Western Aphasia Battery. The assessment was repeated 1 year after stroke.