Depression and major weight gain: a 6-year prospective follow-up of outpatients.

Background: Depression and weight change are linked, but there is a paucity of studies on their association during clinical treatment. The present study investigated how risk factors for a weight gain of at least 10% (major weight gain) and mental health modify their mutual association during a 6-year prospective follow-up of depressed outpatients.

Method: The study sample consisted of 121 depressed treatment-seeking outpatients with a mean age of 44.

Metabolic syndrome and depression: a cross-sectional analysis.

Objective: To examine the prevalence of the metabolic syndrome in depressive outpatients and to identify its correlates in depression.

Method: This cross-sectional analysis was performed on 121 depressive outpatients from January 2002 through January 2004 who were diagnosed at baseline with the Structured Clinical Interview for DSM-III-R. The metabolic syndrome was diagnosed at 6-year follow-up according to the modified criteria of the National Cholesterol Education Program.