Publications by authors named "Kirla Wagner Poti Gomes"
During the COVID-19 pandemic, undergraduate medical students (UMS) exposed to isolation, social distancing and complete or partial face-to-face educational activities interruption may present increased stress, depression and anxiety. This study was undertaken to evaluate if, during isolation, UMS involved in online group activities as investigators of a research project (volunteer group) would present better mental health than their colleagues, not involved in that research (control group). A Web-based survey, via the Google Forms platform, including details on demographic data, life habits, previous health conditions, worries with the COVID-19 pandemic, sleep pattern modifications and depression, anxiety and mental stress, using the DASS-21 (Depression, Anxiety and Stress Scale) was implemented from 20 July to 31 August 2020.
View Article and Find Full Text PDFChronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil.
Adv Rheumatol
October 2021
Article Synopsis
- - The study aimed to investigate the impact of chronic hydroxychloroquine use on COVID-19 incidence among rheumatic disease patients compared to non-users in the same households during the early months of the pandemic in Brazil.
- - Researchers analyzed data from 10,443 participants, finding no significant difference in COVID-19 symptoms between patients on hydroxychloroquine and those not taking it; however, factors like lung disease and systemic sclerosis diagnosis increased risk for COVID-19 in patients.
- - The study highlighted that recent influenza vaccination provided a protective effect against COVID-19, reinforcing the importance of immunization for at-risk populations like those with rheumatic diseases.
Effects of Participating in a Research Project During the COVID-19 Pandemic on Medical Students' Educational Routines and Mental Health: Protocol for a Web-Based Survey Study.
JMIR Res Protoc
April 2021
Article Synopsis
- - The COVID-19 pandemic caused social isolation, negatively affecting medical students' educational routines and mental health, prompting an observational study (MPII) that involved bi-weekly phone calls related to rheumatic diseases.
- - The study aimed to assess the effects of the pandemic and active participation in MPII on medical students' educational experiences and mental health, given their critical training roles in healthcare.
- - A web-based survey compared medical students involved in MPII with their peers, evaluating demographics, perceptions of the study, and mental health outcomes using the DASS-21 scale for depression, anxiety, and stress.
High Prevalence of Metabolic Syndrome in Patients With Psoriatic Arthritis From Northeastern Brazil: Association With Traditional Cardiovascular Risk Factors and Biologic Disease-Modifying Antirheumatic Drugs.
J Clin Rheumatol
September 2021
Article Synopsis
- * Results showed that MetS was significantly more prevalent in PsA patients (53.9%) than in healthy controls (18.4%), and it was linked to conditions like hypertension and elevated blood sugar levels.
- * The study concluded that in PsA patients, MetS is notably prevalent and associated with factors such as the use of specific medications, increased waist circumference, and low levels of good cholesterol (HDL).
High prevalence of obesity in rheumatoid arthritis patients: association with disease activity, hypertension, dyslipidemia and diabetes, a multi-center study.
Adv Rheumatol
October 2019
Article Synopsis
- Rheumatoid arthritis (RA) is linked to cardiovascular disease, and this study investigates how obesity affects inflammation and cardiovascular risks in RA patients.
- The study involved 791 RA patients from Brazil, revealing a high prevalence of obesity (26.9%) and significant cardiovascular risk factors like hypertension and dyslipidemia.
- Findings suggest that obesity is common in RA patients and is associated with higher disease activity and various cardiovascular issues.*
Objectives: To determine the prevalence of metabolic syndrome (MetS) in patients with rheumatoid arthritis (RA) and controls from Northeastern Brazil and to verify its association with specific RA parameters and cardiovascular risk factors.
Methods: The prevalence of MetS was assessed cross-sectionally in 338 RA patients from a single center and 84 age and gender-matched controls from the local community. MetS was defined according to NCEP/ATPIII guidelines.
Leishmaniasis is an anthropozoonosis caused by species of Leishmania and can have different clinical presentations, depending on the parasite-host relationship. Tumor necrosis factor-α (TNF-α) is a cytokine essential to infection control, especially against intracellular parasites such as Leishmania. Anti-TNF-α strategies have had a marked impact on the treatment of rheumatic diseases, but the clinical use of those antagonists has been accompanied by an increased report of infections.
View Article and Find Full Text PDFIt is recommended to evaluate the presence of latent tuberculosis infection (LTBI) prior to the use of antitumor necrosis factor α. The aim of this study is to assess the presence of LTBI in patients with rheumatic diseases undergoing treatment with infliximab in an endemic area for tuberculosis (TB). LTBI was searched through the contact history, chest X-ray and tuberculin skin test with purified protein derivative (PPD) ≥5 mm.
View Article and Find Full Text PDFPsoriatic arthritis (PA) is an inflammatory seronegative arthritis of unknown origin. Classically, PA has five clinical forms, and asymmetric oligoarthritis is the most common type. We describe the case of a patient with PA refractory to disease-modifying drugs, who developed drug-induced hepatitis after chemoprophylaxis with isoniazid, administered prior to the treatment with an anti-TNFα agent.
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