Joint venture surgery of a giant inguinoscrotal hernia in a patient suffering from trisomy 21 and Eisenmenger's syndrome.

A 44-year-old man with Trisomy 21 and Eisenmenger's syndrome underwent surgery due to a life-threatening scrotal hernia, containing the bladder, bilateral hydroceles and part of the sigmoid colon. Joint venture plastic and urologic surgery was performed with reposition of the bladder and sigmoid colon into the abdominal cavity, bilateral inguinal hernial mesh repair, left sided orchiectomy, excision of bilateral hydroceles and excision of a major part of the scrotum and recreation of the original anatomy of the penis and scrotum. This Case presents a successful outcome achieved as the patient after one-step-surgery was left to normal condition.

Clam augmentation enterocystoplasty as management of urge urinary incontinence and reduced bladder capacity.

Third line treatment of urge urinary incontinence (UUI) and/or reduced bladder capacity is bladder augmentation. The aim of this study was to investigate whether clam enterocystoplasty (CECP) was an efficient treatment for patients who were refractory to conservative treatments of UUI and small functional bladder capacity and secondly if there was a difference in outcome in patients with neurogenic and non-neurogenic bladders. We evaluated 118 patients retrospectively treated in the period 2006-2018 at a single university hospital.

Syringocele: a retrospective study and review of the literature.

A syringocele is a cystic dilation of the ducts from the bulbourethral glands located in the bulbous part of the male urethra. It is a rare condition primarily reported in children and young adults. The objective was to evaluate the diagnostic pattern and management strategy in patients of all ages diagnosed with syringocele.

Urinary diversion in the treatment of refractory bladder pain syndrome.

This study investigates the effect of urinary division in patients with bladder pain syndrome (BPS) refractory to conservative treatment. This study aimed to identify pre-operative predictive factors regarding the surgical outcome in patients undergoing urinary diversion with or without cystectomy (CX). This study included 30 patients with BPS treated with a urinary diversion in the period from 2002-2017 at a single university hospital.

Sperm preservation by electroejaculation before anticancer therapy.

Background: This report presents a case where electroejaculation (EEJ) was used for semen cryopreservation (SCP), prior to gonadotoxic anti-cancer treatment in a 14-year old boy diagnosed with Hodgkins disease.

Method: Two sessions of EEJ were performed with an interval of 48 hours.

Results: No complications were seen and the procedures resulted in nine frozen straws of motile spermatozoa.

[Neurogenic autonomic dysfunction in adults].

Neurogenic autonomic dysfunction (NAD) is underdiagnosed, and it is likely in patients, who have orthostatic hypotension and symptoms from multiple organ systems as well as abnormal results from a neurological examination. A clinical and neurophysiological examination of the autonomic nervous system combined with a standardised paraclinical evaluation should be performed. NAD may be present in neurodegenerative disorders, vitamin deficiency, toxicity, infection, and in paraneoplastic, metabolic, hereditary and immune-mediated conditions.

[Neurogenic autonomic dysfunction in primary amyliodosis].

Neurogenic autonomic dysfunction (NAD) and polyneuropathy occur in common conditions like diabetes and alcoholism. However, it can also be seen in rare diseases like in this case report of amyloid light-chain amyloidosis: primary amyloidosis. A 56-year-old man presented with polyneuropathy, a sympathetic dysfunction causing orthostatic intolerance, syncope, parasympathetic dysfunction and involvement of the enteric nervous system.

Single-centre experience with intradetrusor injection of onabotulinumtoxinA: a retrospective study of the years 2003-2012 in a Danish population.

Objective: This study aimed to evaluate the efficacy of treatment for incontinence due to neurogenic detrusor overactivity (NDO) and idiopathic detrusor overactivity (IDO) with onabotulinumtoxinA (BoNT-A) at Aarhus University Hospital, Skejby, Denmark.

Materials And Methods: The data were collected retrospectively by systematic review of the patient records from March 2003 to May 2012. Patients treated with BoNT-A over the age of 18 years were included.

Contralateral testicular cancer despite negative biopsy 30 months earlier.

Contralateral testis biopsy in patients with unilateral testis germ cell cancer is a controversial topic. We present a case of a young male who develops a second testis germ cell cancer despite negative biopsy 30 months earlier. A review of the newest studies and the Scandinavian and European guidelines concerning contralateral testis biopsy is performed.

Yang-Monti ileal ureter reconstruction.

Objective: The aim of this study was to present experience with ureteral reconstruction using the Yang-Monti technique with reconfigured ileal segments.

Material And Methods: Between 2006 and 2010, five patients underwent complete unilateral ureteral substitution with the Yang-Monti technique, whereby short segments of ileum were incised paramesenterically, joined and transversely tubularized to form a neoureter of suitable length and cross-sectional diameter to bridge large ureteral defects. The causes of the ureteral defects were strictly iatrogenic.

Flow-evoked vasodilation is blunted in penile arteries from Zucker diabetic fatty rats.

Introduction: Endothelium-derived relaxing factors such as nitric oxide (NO), prostanoids, and endothelium-derived hyperpolarizing factor (EDHF) are thought to play an important role in vasodilation of penile arteries.

Aim: The present study investigated the mechanisms involved in flow- and acetylcholine-induced vasodilation in penile arteries, and whether acetylcholine- and flow-mediated vasodilation is altered in Zucker diabetic fatty (ZDF) rats, a model of type 2 diabetes. Moreover, it was addressed whether enhanced myogenic tone may explain impaired flow-evoked vasodilation in arteries from ZDF rats.

NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats.

Background And Purpose: Large-conductance Ca(2+)-activated K(+) channels (BK(Ca)), located on the arterial and corporal smooth muscle, are potential targets for treatment of erectile dysfunction (ED). This study investigated whether NS11021 (1-(3,5-Bis-trifluoromethyl-phenyl)-3-[4-bromo-2-(1H-tetrazol-5-yl)-phenyl]-thiourea), a novel opener of BK(Ca) channels, relaxes erectile tissue in vitro and enhances erectile responses in intact rats. The effects were compared with sildenafil, an inhibitor of phosphodiesterase type 5.

[Urinary incontinence after prostatic surgery].

The prevalence of stress urinary incontinence after prostatic surgery for benign disease is 0-2% and 5-35% after surgery for malignant disease. After radical prostatectomy for prostate cancer spontaneous improvement of stress incontinence occurs up to 1 year after surgery. Medical treatment with doloxetine (a serotonine-noradrenaline-reuptake inhibitor) and minimal invasive treatments like urethral bulking and male sling procedures are only effective against minor stress incontinence.

Non-Fournier's gangrene of the penis: Report of two cases and review of the literature.

Dry gangrene of the penis due to ischaemia is a rare condition. In cases previously reported in the literature, the aetiology was end-stage renal failure in combination with severe arteriosclerosis and diabetes mellitus. We present herein two cases of dry gangrene of the penis with two different aetiologies.

Clinical experience with the Mentor Alpha-1 inflatable penile prosthesis: report on 65 patients.

Objective: To evaluate the complications and prosthesis survival associated with implantation of the Mentor Alpha-1 inflatable penile prosthesis (IPP) for the treatment of erectile dysfunction (ED).

Material And Methods: Between August 1995 and March 2003, 65 patients underwent implantation of a Mentor Alpha-1 IPP at the Urological Departments of Skejby or Aalborg University Hospitals. Patient data were obtained retrospectively from medical files.

Conditional stimulation of the dorsal penile/clitoral nerve may increase cystometric capacity in patients with spinal cord injury.

Aims: To investigate the feasibility of conditional short duration electrical stimulation of the penile/clitoral nerve as treatment for detrusor hyperreflexia, the present study was initiated.

Methods: Ten patients with spinal cord injury, 4 women and 6 men, with lesions at different levels above the sacral micturition center had a standard cystometry performed. During a subsequent cystometry, conditional short duration electrical stimulation of the penile/clitoral nerve was performed as treatment for one or more detrusor hyperreflexic contractions.

Rehabilitation of long-term sick-listed patients in Sweden through techniques of sports medicine.

Sweden has seen a sharp increase in sick-listing recently. A new rehabilitation programme was tested for patients with musculoskeletal pain applying the experiences from sports injury rehabilitation. In this programme, the danger of inactivity was emphasised, and the staff accepted that the process of restoring physical fitness may be accompanied by a temporary increase in pain.

Insulinoma diagnosed by endoscopic ultrasonography-guided biopsy.

Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a new technique that seems to expand the utility of EUS, making definitive diagnosis of pancreatic lesions possible. However, the exact indications for the method, as well as its limitations, are not fully defined. We report on a patient with an insulinoma in the tail of the pancreas undetected by other imaging modalities that was conclusively diagnosed by EUS-FNA.

Efficacy and safety of fixed-dose oral sildenafil in the treatment of erectile dysfunction of various etiologies.

Objectives: To determine the efficacy and safety of fixed-dose oral sildenafil in patients with erectile dysfunction (ED) of various etiologies.

Methods: In a 12-week, double-blind, randomized, placebo-controlled, fixed-dose study, 514 men (mean age 56 years) with ED were randomized to receive 25, 50, or 100 mg of sildenafil or placebo. The primary etiology of ED was determined to be organic in 32% of men, psychogenic in 25%, or mixed in 43%.