[The characteristics of the endocrine function of the fetoplacental system in pregnant women with chronic pyelonephritis and nephropathy].

A follow-up study of 100 pregnant women with chronic pyelonephritis and superimposed nephropathy has shown that the major determinant of placental insufficiency is late toxemia of pregnancy, not the underlying disease. Estriol levels correlated with severity and duration of gestosis and thus provided the best predictor of fetoplacental insufficiency. Findings on placental lactogen production were less helpful since the production of this hormone was decreased only in severe nephropathy.

[Status of the utero-placental blood circulation in pregnant women with chronic pyelonephritis and nephropathy].

Dynamic scintigraphy was employed in studying of uteroplacental blood flow in 75 pregnant females with variety of nephropathic severity and duration developing in presence of chronic pyelonephritis. Hemodynamic disorders in the mother-placental system in females with associated gestosis were found to depend both on its severity and duration. In females with continuous severe nephropathy the most pronounced hemodynamic impairment was revealed at the late pregnancy, (37-38 weeks of gestation).