[Genome instability in pulmonary tuberculosis before and after treatment].

Pulmonary tuberculosis is classified as a disease with a genetic predisposition, and therefore, as with other pathologies related to this group of diseases, by pulmonary tuberculosis, special importance is given to finding those markers that enable early identification of risk groups, such as skrinnig in general population and relatives of patients with tuberculosis, which in turn can provide the basis for preventive measures. One of this markers is the level of genome stability. The aim of this study was a comparative evaluation of the functional parameters of the genome variability in patients with sensitive form of pulmonary tuberculosis before and after treatment, and the possibility of its correction with anti-stress peptide bioregulator - epitalon.

[Study of epidemiological situation of HIV associated TB in Georgia].

The goal of the work is to study epidemiological situation of TB/HIV coinfection in Georgia. The research was based on the study of TB prevalence among 766 HIV/AIDS patients registered at the National Centre of Infections Diseases, AIDS and Clinical Immunology in 1989-2004; determining of HIV status among 3084 patients with active TB, treated in the hospital of the National Centre of TB and Lung Diseases, Abastumani TB-hospital and Ksani prison Analysis of the obtained data showed that dynamic of TB/HIV coinfection in the period of 2000-2004 varied from 2,1% to 3,8%. Results show low indicators of HIV associated TB prevalence in Georgia.