[Assessment of sugammadex use efficiency and safety for neuromuscular block reversion].

Blockade of neuromuscular conductivity is a considered one of basic part of a patient protection in a concept of a balanced multicomponent anesthesia. The controlled neuromuscular paralysis in a combination of a sedation, an analgesia and a hyporeflection not only provides comfortable conditions to surgeons for carrying out surgeries, but also allows to manage a gas exchange, blood circulation and a metabolism in a patient. However in clinical practice there is such complication after application of muscular relaxant (not depolarizing) as a residual curarization.

[Exogenous activated protein C in severe sepsis].

Exogenous activated protein C combines a marked anti-inflammatory effect on the vascular endothelium and anticoagulative and profibrinolytic activities. The total results of this action are better multiple organ microcirculation and, as a result, elimination and even prevention of irreversible changes in the vitally important organs. The many-sidedness and potency of this effect make the agent essential for intensive therapy of severe sepsis of various etiology.

[Comparative estimation of effectiveness of nonsteroidal anti-inflammatory drugs used for postoperative pain management].

A comparative analysis of the analgetic and side effects of Ketonal, Ketoral and Diklogen was performed during treatment of 64 patients. Ketonal was found to have more pronounced analgetic effect and minimal side effects.

[Comparative study of the use of mivacron and tracrium in anesthesia during laparoscopic cholecystectomy].

Two nondepolarizing myorelaxants: tracrium, with medium-long duration of action, and a new short-acting drug mivacron were used in combined anesthesia of 50 patients with gastrointestinal diseases subjected to laparoscopic cholecystectomy. Both drugs can be used for anesthesia of laparoscopic operations; mivacron should be preferred due to its shorter action.