Comparison of frequency of wound infection: open vs laparoscopic cholecystectomy.

Background: The objective of this quasi experimental study was to compare the frequency of wound infection between open cholecystectomy (OC) and laparoscopic cholecystectomy (LC) conducted in Surgical Unit IV, Jinnah Hospital Lahore from June 2005 to January 2006.

Methods: 100 patients undergoing elective cholecystectomy for symptomatic gallstones were studied. The patients were allocated in the two groups of 50 each by simple random technique.

Anti-neurofilament antibodies in neuropathy with monoclonal gammopathy of undetermined significance produce experimental motor nerve conduction block.

Elevated levels of serum antibodies to neurofilament proteins have been associated with a variety of neurological diseases, including autoimmune disorders such as neuropathy with monoclonal gammopathy of undetermined significance (MGUS). The pathological significance of anti-neurofilament antibodies in sera of affected patients, however, remains unclear. In this study, we report our findings of polyclonal antibodies in sera from 4 of 16 IgG MGUS neuropathy patients that react strongly on immunoblot with a high molecular weight neurofilament protein (NFH).