Electrophysiological and Visual Parameter Changes in Retinitis Pigmentosa Patients undergoing Autologous Platelet-Rich Plasma Therapy: A Randomized Control Trial.

Purpose: To assess the efficacy of autologous platelet-rich plasma (PRP) injections in suprachoroidal space and subtenon space in cases of retinitis pigmentosa, which is a genetic disease, leading to gradual loss of vision. Till date, no treatment is available.

Methods: Seventy-eight eyes of 39 patients of retinitis pigmentosa having visual acuity ranging from reading of Early Treatment Diabetic Retinopathy Study (ETDRS) chart from 1 m onward to patients who were not able to read the ETDRS chart but whose visual acuity ranged from finger count close to face to <1 m were included in the study.

Optimum design and performance of a base-isolated structure with tuned mass negative stiffness inerter damper.

In order to increase the efficiency of the structures to resist seismic excitation, combinations of inerter, negative stiffness, and tuned mass damper are used. In the present work, the optimum tuning frequency ratio and damping of the tuned mass negative stiffness damper-inerter (TMNSDI) for the base-isolated structure were determined by employing the numerical searching technique under filtered white-noise earthquake excitation and stationary white noise. The energy dissipation index, the absolute acceleration, and the relative displacement of the isolated structure were considered as the optimum parameters, obtained by their maximization.

Production of surfactant and detergent-stable, halophilic, and alkalitolerant alpha-amylase by a moderately halophilic Bacillus sp. Strain TSCVKK.

A moderately halophilic alkalitolerant Bacillus sp. Strain TSCVKK, with an ability to produce extracellular halophilic, alkalitolerant, surfactant, and detergent-stable alpha-amylase was isolated from soil samples obtained from a salt-manufacturing industry in Chennai. The culture conditions for higher amylase production were optimized with respect to NaCl, substrate, pH, and temperature.