Metabolic adaptation to caloric restriction and subsequent refeeding: the Minnesota Starvation Experiment revisited.

Background: Adaptive thermogenesis (AT) is the fat-free mass (FFM)-independent reduction of resting energy expenditure (REE) to caloric restriction (CR). AT attenuates weight loss and favors weight regain. Its variance, dynamics, and control remain obscure.

Relationship between submaximal oxygen uptake, detailed body composition, and resting energy expenditure in overweight subjects.

Objective: We investigated the impact of detailed body composition on aerobic fitness to determine whether regional components of fat mass have independent effects on VO2submax , and whether VO2submax and detailed body composition independently explain variation in REE.

Methods: 71 healthy adults (80% female, 20% male, BMI 28.2-43.

Influence of partial sleep deprivation on energy balance and insulin sensitivity in healthy women.

Background: Voluntary sleep restriction is a lifestyle feature of modern societies that may contribute to obesity and diabetes. The aim of the study was to investigate the impact of partial sleep deprivation on the regulation of energy balance and insulin sensitivity.

Subjects And Methods: In a controlled intervention, 14 healthy women (age 23-38 years, BMI 20.

Health-related quality of life in children and adolescents with asthma: results from the ESTAR Study.

Our aim was to assess the psychosocial well-being of asthmatic children and adolescents, the influencing factors, and to determine the effect of inpatient rehabilitation on their quality of life; 226 asthmatic children and adolescents participated in the inpatient rehabilitation (IG). The comparison group (CG) included 92 asthmatic children and adolescents receiving standard medical treatments. Patients were aged between 8 and 16 years and were predominantly male.

[Long-term effect of indoor rehabilitation on children and young people with moderate and severe asthma].

In a multi-centre trial the effect of indoor rehabilitation in case of bronchial asthma in childhood and adolescence was evaluated on a prospective basis in comparison to an ambulant group of patients. 195 children and adolescents aged between 8 and 16 suffering from bronchial asthma (grading of severity 3 and 4) were included in the trial. The rehabilitation group (RG) included 149 patients, whereas the out-patient reference group consisted of 46 patients.

[Antibiotic pharmacokinetics in patients with mucoviscidosis].

In this review we summarize the available literature on the pharmacokinetics of antibacterials in cystic fibrosis. A special impact is given on the results of our group which will be put in perspective with the results of other authors. The homogeneity of our patient population allows a valid comparison between patient and volunteer data.

[Latex and coagglutination test of serum and urine in childhood pneumonia].

41 children with pneumonia (proven by X-ray) and 271 children with upper respiratory tract infections were examined for bacterial antigens (Haemophilus influenzae type b and pneumococci) in serum and urine. In patients with pneumonia blood cultures, deep nasal swabs and antibody assay in serum (against Mycoplasma pneumoniae and Chlamydia) were made. In 271 patients with an upper respiratory tract infection also a deep nasal swab for bacterial cultures was performed.

[Air pathogen content in the intensive care station of a pediatric clinic].

The bacterial count of air in 2 intensive care units was examined by membrane filter technique (MD 2 model SM 167 21). 88 samples of room air and 296 samples of incubator air were studied. The occurrence of bacteria, especially gramnegative rods, was investigated in incubators and in respirators.

In vitro comparison of fluid blood culture media.

Eight fluid blood culture media from different manufacturers were compared with regard to their ability to culture fastidious microorganisms. In turbidity measurements following inoculation with different bacteria, the media differed with respect to the duration of the lag phase and the log phase of bacterial growth. Similar differences were observed with small inocula in original blood culture bottles (commercially available).

[An optimal blood culture technic].

For blood cultures in septicemic patients it is advisable to use two broth culture bottles. One bottle should be incubated with air, the other without (for anaerobes). Supplemented Peptone Broth II (Becton-Dickinson) and BHI Roche were superior for culturing aerobic and anaerob bacteria in comparison to other blood culture media.

[Occurrence and diagnosis of Chlamydia trachomatis infections in newborns and young infants (author's transl)].

Chlamydia trachomatis was assayed using McCoy cell culture on vaginal swabs from pregnant women and on conjunctival and nasopharyngeal swabs from newborns. C. trachomatis was found in 23 of 168 pregnant women (8%) and in 15 of 298 newborns (5%).

Serum concentrations of vitamin E in healthy infants fed commercial milks.

Serum vitamin E concentrations were determined in 60 term and 26 premature infants during the first 2 months of life. All infants received commercial milk formula containing vitamin E. In addition, premature infants older than 10 days were given vitamin E orally as a multivitamin preparation.

[The plasma-protein-binding of Clindamycin Cephazolin and Cephradin in neonates and adults (author's transl)].

In pooled serum of 12 healthy adults and 12 neonates (blood taken from the umbilical cord) the free and protein-bound parts of Cephazolin, Cephradin and Clindamycin were tested by equilibrium dialysis in relation to the concentration of the antibiotic. In the serum of adults at a concentration of 36 mcg/ml the free part of Cephazolin amounted to 16%, at a concentration of 35 mcg/ml the free Cephradin was 87%, at a concentration of 97 mcg/ml the free Clindamycin was 16%. The binding constant k of Cephazolin was 12.