Importance: In 2014, Maryland initiated the global budget revenue (GBR) model, placing caps on total hospital expenditures across all care sites. The GBR program aims to reduce unnecessary utilization while maintaining or improving care quality. To date, there has been limited examination of program effects on cancer care.
View Article and Find Full Text PDFIn the first year of Maryland's experiment in setting all-payer rates for hospital services, costs were contained and the quality of care improved, though the state still has high rates of hospital admissions and per capita spending for Medicare patients.
View Article and Find Full Text PDFThere are limited data on the use of steroids and antibiotics in assisted reproductive technology (ART). Our aim was to evaluate the impact of these treatments on the outcome of IVF cycles in which Assisted Hatching (AH) was performed. We studied a retrospective cohort in a large university-affiliated infertility centre.
View Article and Find Full Text PDFObjective: To assess whether total reproductive potential (TRP), the chance of a live birth from each fresh cycle (fresh cycle plus frozen transfers), could be calculated from the national Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database and whether information not available in SART CORS resulted in significant changes to the TRP calculation.
Design: Retrospective study using SART CORS and clinic data.
Setting: Three assisted reproductive technology clinics.
Objective: To determine the prognosis for clinical pregnancy and delivery after total fertilization failure.
Design: Retrospective analysis of patient treatment cycles.
Setting: Private fertility clinic.
Extracellular matrices and their associated growth factors can modulate the in-vitro growth of cells. In this study, the effects of culture substrata and the cytokine interleukin-6 (IL-6) on embryonic development were investigated. In-vitro fertilized mouse oocytes were pooled and randomly distributed amongst treatment groups.
View Article and Find Full Text PDFThis study was designed to provide further information on mouse and human embryo development in alpha-modified minimum essential medium (alphaMEM). First, we compared the development and implantation potential of murine in-vitro fertilized (IVF) embryos cultured in alphaMEM, in the presence and absence of co-culture cells. No significant difference was observed in blastocyst rate between alphaMEM alone (76.
View Article and Find Full Text PDFObjective: To determine attitudes regarding multiple pregnancy and multifetal pregnancy reduction in couples embarking on gonadotropin therapy.
Design: Questionnaire given to couples initiating gonadotropin therapy.
Setting: University hospital-based infertility unit.
The proportion and quality of motility of spermatozoa in normozoospermic ejaculates were assessed using computer-assisted semen analysis. The ejaculate was split and the motility re-assessed following separation on a Percoll gradient with or without cryomedium and cryopreservation. Cryopreservation caused a significant decrease in the proportion of motile spermatozoa and in their velocity and amplitude of lateral head displacement.
View Article and Find Full Text PDFExtracellular ATP in concentrations of 0.5 to 2.5 mM modulates TNF-induced cytolysis of L929 cells in the presence of actinomycin D.
View Article and Find Full Text PDFCollections of Amblyomma americanum (L.) from five habitat types showed that significantly more ticks of all life stages could be collected by CO2-baited sticky traps than by the standard flagging technique. The effect of habitat type and season significantly influenced the number of ticks collected by both techniques.
View Article and Find Full Text PDFThe provider and financing segments of health care are now in a "destabilization" phase, using Eli Ginsberg's perfectly descriptive term. Even with the lowest unemployment levels in years, the numbers of people who have no health insurance, most of them employed, keep going up. The health sector has been on a competitive binge that was supposed to contain cost increases, but aggregate expenditures for health care are rising on about the same curve as before.
View Article and Find Full Text PDFA strong case can be made for restructuring the health care delivery system using a vertically integrated model. The difficulties with such a voluntary effort surface with a review of 12 laws of hospital interaction.
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